parathyroid hormone (7-34) [Homo sapiens]/[Macaca fascicularis]
Referência TP2283-5mg
Tamanho : 5mg
Marca : TargetMol
parathyroid hormone (7-34) [Homo sapiens]/[Macaca fascicularis]
Copy Product Infoparathyroid hormone (7-34) [Homo sapiens] [Macaca fascicularis] is a peptide with the sequence H2N-LMHNLGKHLNSMERVEWLRKKLQDVHNF-OH, MW= 3474.03. Parathyroid hormone (PTH) is secreted by the chief cells of the parathyroid glands as a polypeptide containing 84 amino acids. It acts to increase the concentration of calcium (Ca2+) in the blood, PTH acts to increase the concentration of calcium in the blood by acting upon the parathyroid hormone 1 receptor and the parathyroid hormone 2 receptor.
![parathyroid hormone (7-34) [Homo sapiens]/[Macaca fascicularis]](/proxy_img/aHR0cHM6Ly9jZG4udGFyZ2V0bW9sLmNvbS9ncm91cDMvTTAwL0EyLzdEL0Nnb2FFV252VUtHRUJJR3JBQUFBQU5mSHYyWTA0Ni5wbmc=.png)
For research use only—not for human use. No sales to individuals. Use as intended only.
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | parathyroid hormone (7-34) [Homo sapiens] [Macaca fascicularis] is a peptide with the sequence H2N-LMHNLGKHLNSMERVEWLRKKLQDVHNF-OH, MW= 3474.03. Parathyroid hormone (PTH) is secreted by the chief cells of the parathyroid glands as a polypeptide containing 84 amino acids. It acts to increase the concentration of calcium (Ca2+) in the blood, PTH acts to increase the concentration of calcium in the blood by acting upon the parathyroid hormone 1 receptor and the parathyroid hormone 2 receptor. |
| In vitro | PTH reduces the reabsorption of phosphate from the proximal tubule of the kidney, which means more phosphate is excreted through the urine. PTH enhances the uptake of phosphate from the intestine and bones into the blood. In the bone, slightly more calcium than phosphate is released from the breakdown of bone. In the intestines, absorption of both Calcium and Phosphate is mediated by an increase in activated vitamin D [1][2]. |
| Molecular Weight | 3474.03 |
| Formula | C154H246N48O40S2 |
| Relative Density. | no data available |
| Sequence | H-Phe-Met-His-Asn-Leu-Gly-Lys-His-Leu-Ser-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asp-Phe-NH₂ |
| Sequence Short | FMHNLGKHLSSMERVEWLRKKLQDVHDF |
| Storage | Keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO: ≥347.4 mg/mL, Sonication is recommended. |