Rat FATP1 (Fatty Acid Transport Protein 1) Sandwich ELISA Kit E0008802)

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	Slc27a1Uniprot ID=S27A1_RAT"
Sample Type:	tissue homogenates, cell lysates or other biological fluids.

Tissue Specificity	Expressed in muscle.
Post Translational Modifications
Function	Mediates the import of long-chain fatty acids (LCFA) into the cell by facilitating their transport at the plasma membrane. Also functions as an acyl-CoA ligase catalyzing the ATP-dependent formation of fatty acyl-CoA using LCFA and very-long-chain fatty acids (VLCFA) as substrates, which prevents fatty acid efflux from cells and might drive more fatty acid uptake. May act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane-associated multimeric protein complex to trap and draw fatty acids towards accumulation. Plays a pivotal role in regulating available LCFA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism. Probably involved in fatty acid transport across the blood barrier.
Protein Name	Long-Chain Fatty Acid Transport Protein 1 Arachidonate--Coa Ligase Fatty Acid Transport Protein Fatty Acid Transport Protein 1 Fatp-1 Long-Chain-Fatty-Acid--Coa Ligase Solute Carrier Family 27 Member 1 Very Long-Chain Acyl-Coa Synthetase
Database Links
Cellular Localisation	Cell Membrane Single-Pass Membrane Protein Endomembrane System Cytoplasm Plasma Membrane And Intracellular Membranes At Least In Adipocytes In Adipocytes But Not Myocytes Insulin Via The Mtorc1 Signaling Pathway Induces A Rapid Translocation Of Slc27a1 From Intracellular Compartments To The Plasma Membrane Paralleled By Increased Lcfa Uptake Insulin-Dependent Translocation From The Cytoplasm To The Cell Membrane Is Regulated By Eprs1 Predominantly Cytoplasmic In Myocytes
Alternative ELISA Names	Long-Chain Fatty Acid Transport Protein 1 ELISA kit Arachidonate--Coa Ligase ELISA kit Fatty Acid Transport Protein ELISA kit Fatty Acid Transport Protein 1 ELISA kit Fatp-1 ELISA kit Long-Chain-Fatty-Acid--Coa Ligase ELISA kit Solute Carrier Family 27 Member 1 ELISA kit Very Long-Chain Acyl-Coa Synthetase ELISA kit Slc27a1 ELISA kit Fatp ELISA kit Fatp1 ELISA kit
output

Information sourced from Uniprot.org

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