Recombinant Animal Free Human EGF protein
Referência MBS206888-0,1mg
Tamanho : 0.1mg
Marca : MyBiosource
3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.
Human EGF stimulates cell proliferation of the Balb/3T3 mouse embryonic fibroblast cells. The ED50 range <= 0.1 ng/ml.
EGF Animal Free Human Active Protein
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS206888Recombinant human epidermal growth factor (EGF) is a 6. 3 kDa globular protein containing 54 amino acids residues, including 3 intra-molecular disulfide bonds. EGF is a potent growth factor that stimulates the proliferation of various epidermal and epithelial… More details
Product Overview
Online Datasheet in PDFProduct Name
EGF, Active Protein
Full Product Name
Recombinant Animal Free Human EGF protein
Product Gene Name
EGF active protein
Product Synonym Names
Epidermal growth factor; Pro-epidermal growth factor; urogastrone; EGF
Sequence
MNSDSECPLS HDGYCLHDGV CMYIEALDKY ACNCVVGYIG ERCQYRDLKW WELR
Host
E coli
Form/Format
Liquid in. Phosphate-Buffered Saline (pH7.4)
Purity/Purification
> 95% by SDS-PAGE
Concentration
1mg/ml (determined by Bradford assay) (lot specific)
Preparation and Storage
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
129,746 Da
Sequence Positions
971-1023aa
OMIM
gene 611718
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Species
Human
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Product Categories/Family for EGF active protein
Hormones & Cytokines; Proteins
Applications Tested/Suitable for EGF active protein
SDS-PAGE (SDS), Bioactivity
Product References and Citations for EGF active protein
Riese., et al (1998) Bioessays. 20: 41-48.
Cohen S., (1983) Cancer. 15: 1787-1791.
Carpenter G., et al (1979) Annu. Rev. Biochem., 48: 193-216.
Cohen S., (1983) Cancer. 15: 1787-1791.
Carpenter G., et al (1979) Annu. Rev. Biochem., 48: 193-216.
Other Notes
Small volumes of EGF active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for EGF purchase
MBS206888 is an active protein targeting EGF. Also known as Recombinant Animal Free Human EGF protein. Host: E coli.
Additional Details
NCBI/Uniprot data below describe general gene information for EGF. It may not necessarily be applicable to this product.
NCBI Official Full Name
pro-epidermal growth factor isoform 1 preproprotein
NCBI Official Synonym Full Names
epidermal growth factor
NCBI Official Symbol
EGF
NCBI Official Synonym Symbols
URG; HOMG4
UniProt Protein Name
Pro-epidermal growth factor
UniProt Synonym Protein Names
Urogastrone
Protein Family
Pro-epidermal growth factor
UniProt Gene Name
EGF
UniProt Synonym Gene Names
EGF
UniProt Entry Name
EGF_HUMAN
NCBI Protein Information
pro-epidermal growth factor; beta-urogastrone
NCBI Summary for EGF
This gene encodes a member of the epidermal growth factor superfamily. The encoded protein is synthesized as a large precursor molecule that is proteolytically cleaved to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding the high affinity cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Show more Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with EGF active protein
| Reference Product | PubMed Publications |
|---|---|
| EGFR active protein | >5672 publications with EGF and EGFR |
| ERBB2 active protein | >1355 publications with EGF and ERBB2 |
| SRC active protein | >1236 publications with EGF and SRC |
| ERBB4 active protein | >407 publications with EGF and ERBB4 |
| GRB2 active protein | >362 publications with EGF and GRB2 |
| STAT3 active protein | >298 publications with EGF and STAT3 |
| ERBB3 active protein | >276 publications with EGF and ERBB3 |
| ADAM17 active protein | >116 publications with EGF and ADAM17 |
| FN1 active protein | >8 publications with EGF and FN1 |
Pathways associated with EGF active protein
| Products by Pathway | Pathway Diagram |
|---|---|
| Adaptive Immune System Pathway antibodies | Adaptive Immune System Pathway Diagram |
| Arf6 Signaling Events Pathway antibodies | Arf6 Signaling Events Pathway Diagram |
| Bladder Cancer Pathway antibodies | Bladder Cancer Pathway Diagram |
| Bladder Cancer Pathway antibodies | Bladder Cancer Pathway Diagram |
| Ceramide Signaling Pathway antibodies | Ceramide Signaling Pathway Diagram |
| Choline Metabolism In Cancer Pathway antibodies | Choline Metabolism In Cancer Pathway Diagram |
| Choline Metabolism In Cancer Pathway antibodies | Choline Metabolism In Cancer Pathway Diagram |
| Constitutive PI3K/AKT Signaling In Cancer Pathway antibodies | Constitutive PI3K/AKT Signaling In Cancer Pathway Diagram |
| Constitutive Signaling By EGFRvIII Pathway antibodies | Constitutive Signaling By EGFRvIII Pathway Diagram |
| Constitutive Signaling By Ligand-Responsive EGFR Cancer Variants Pathway antibodies | Constitutive Signaling By Ligand-Responsive EGFR Cancer Variants Pathway Diagram |
Diseases associated with EGF active protein
| Disease Name | Pubmed Publications |
|---|---|
| Breast Neoplasms Antibodies | >1686 publications with EGF and Breast Neoplasms |
| Adenocarcinoma Antibodies | >1327 publications with EGF and Adenocarcinoma |
| Necrosis Antibodies | >1006 publications with EGF and Necrosis |
| Neoplasms, Experimental Antibodies | >893 publications with EGF and Neoplasms, Experimental |
| Cell Transformation, Neoplastic Antibodies | >876 publications with EGF and Cell Transformation, Neoplastic |
| Lung Neoplasms Antibodies | >853 publications with EGF and Lung Neoplasms |
| Inflammation Antibodies | >736 publications with EGF and Inflammation |
| Neoplasm Metastasis Antibodies | >645 publications with EGF and Neoplasm Metastasis |
| Liver Diseases Antibodies | >575 publications with EGF and Liver Diseases |
| Neoplasm Invasiveness Antibodies | >559 publications with EGF and Neoplasm Invasiveness |
Organs/Tissues associated with EGF active protein
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Brain Antibodies | >1877 publications with EGF and Brain |
| Lung Antibodies | >1812 publications with EGF and Lung |
| Kidney Antibodies | >1617 publications with EGF and Kidney |
| Skin Antibodies | >1431 publications with EGF and Skin |
| Muscle Antibodies | >1346 publications with EGF and Muscle |
| Embryonic Tissue Antibodies | >1127 publications with EGF and Embryonic Tissue |
| Eye Antibodies | >929 publications with EGF and Eye |
| Intestine Antibodies | >912 publications with EGF and Intestine |
| Mouth Antibodies | >873 publications with EGF and Mouth |
| Placenta Antibodies | >467 publications with EGF and Placenta |