Reagentes e instrumentos para imunologia, biologia celular e biologia molecular.
 
> Sterigmatocystine [10048-13-2]

Sterigmatocystine [10048-13-2]

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Referência T16942-1mg

Tamanho : 1mg

Marca : TargetMol


Sterigmatocystine

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Sterigmatocystine is an inhibitor of G1 Phase and DNA synthesis and is used to inhibit p21 activity. Sterigmatocystine is a precursor of aflatoxins and a mycotoxin produced by common mold strains from Aspergillus versicolor.
Sterigmatocystine
Cas No. 10048-13-2
For research use only—not for human use. No sales to individuals. Use as intended only.

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Product Information

Bioactivity
Description
Sterigmatocystine is an inhibitor of G1 Phase and DNA synthesis and is used to inhibit p21 activity. Sterigmatocystine is a precursor of aflatoxins and a mycotoxin produced by common mold strains from Aspergillus versicolor.
In vitro
Sterigmatocystine-induced DNA damage activates the ATM/53-dependent signaling pathway, leading to G2 arrest in GES-1 cells [4].
In vivo
Sterigmatocystine (ip; 3 mg/kg once daily for 14 days) suppresses p21WAF1/CIP1 [3].
Chemical Properties
Molecular Weight324.2843
FormulaC18H12O6
Cas No.10048-13-2
SmilesCOC1=CC2=C([C@@H]3C=CO[C@@H]3O2)C2=C1C(=O)C1=C(O2)C=CC=C1O
Relative Density.1.51 g/cm3
Storage & Solubility Information
StorageKeep away from direct sunlight, Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.