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> Tau Protein, Rat, Recombinant (His)

Tau Protein, Rat, Recombinant (His)

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Referência NB-64-52005-200ug

Tamanho : 200ug

Marca : Neo Biotech


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Tau Protein, Rat, Recombinant (His)

(Synonyms: Tau, Paired helical filament-tau (PHF-tau), Neurofibrillary tangle protein, Mtapt, Microtubule-associated protein tau, Mapt) Copy Product Info

Synonyms: Tau, Paired helical filament-tau (PHF-tau), Neurofibrillary tangle protein, Mtapt, Microtubule-associated protein tau, Mapt

Catalog No. TMPH-03336 Copy Product Info
Tau Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with N-10xHis tag. The predicted molecular weight is 81.2 kDa and the accession number is P19332.
Other Forms of Tau Protein, Rat, Recombinant (His):
Tau Protein, Rhesus macaque, Recombinant (His & SUMO)
Tau Protein, Rhesus macaque, Recombinant (His)
Tau Protein, Mouse, Recombinant (His)
Tau Protein, Rat, Recombinant (E. coli, His)
Fetal-tau Protein, Human, Recombinant (His)
For research use only—not for human use. No sales to individuals. Use as intended only.

Product Introduction

Bioactivity
Bioactivity
Measured by its binding ability in a functional ELISA. Immobilized Rat Mapt at 2 μg/mL can bind anti-MAPT recombinant antibody, the EC 50 is 136.2-238.9 ng/mL.
Description
Tau Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with N-10xHis tag. The predicted molecular weight is 81.2 kDa and the accession number is P19332.
Species
Rat
Expression System
HEK293 Cells
TagN-10xHis
Accession NumberP19332
Amino AcidAEPRQEFDTMEDQAGDYTMLQDQEGDMDHGLKESPPQPPADDGSEEPGSETSDAKSTPTAEDVTAPLVEERAPDKQATAQSHTEIPEGTTAEEAGIGDTPNMEDQAAGHVTQEPQKVEIFSQSLLVEPGRREGQAPDSGISDWTHQQVPSMSGAPLPPQGLREATHQPLGTRPEDVERSHPASELLWQESPQKEAWGKDRLGSEEEVDEDITMDESSQESPPSQASLAPGTATPQARSVSASGVSGETTSIPGFPAEGSIPLPADFFSKVSAETQASPPEGPGTGPSEEGHEAAPEFTFHVEIKASAPKEQDLEGATVVGAPAEEQKARGPSVGKGTKEASLLEPTDKQPAAGLPGRPVSRVPQLKARVAGVSKDRTGNDEKKAKTSTPSCAKTPSNRPCLSPTRPTPGSSDPLIKPSSPAVCPEPATSPKYVSSVTPRNGSPGTKQMKLKGADGKTGAKIATPRGAATPGQKGTSNATRIPAKTTPSPKTPPGSGEPPKSGERSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSASKSRLQTAPVPMPDLKNVRSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVHIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL
Construction2-752 aa
Protein Purity
> 95% as determined by SDS-PAGE.
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
ReconstitutionReconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsTau, Paired helical filament-tau (PHF-tau), Neurofibrillary tangle protein, Mtapt, Microtubule-associated protein tau, Mapt
Research Background
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Chemical Properties
Molecular Weight81.2 kDa (predicted)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

PHF-tauPHFtau
Related Tags: Tau Protein, Rat, Recombinant (His) chemical structure | Tau Protein, Rat, Recombinant (His) molecular weight