trans-Zeatin [1637-39-4]
Referência NB-64-61777-25mg
Tamanho : 25mg
Marca : Neo Biotech
trans-Zeatin (Synonyms: (E)-Zeatin)
Catalog No. TMS2181 Copy Product Info
Purity: 98.96%
trans-Zeatin ((E)-Zeatin) is the member of the plant growth hormone family known as cytokinins, which regulate cell division, development, and nutrient processing.
trans-Zeatin
Copy Product InfoSynonyms (E)-Zeatin
trans-Zeatin ((E)-Zeatin) is the member of the plant growth hormone family known as cytokinins, which regulate cell division, development, and nutrient processing.
Cas No. 1637-39-4
Product Introduction
trans-Zeatin AI Summary
trans-Zeatin exhibits diverse bioactivities across several biological systems and assays. In plants, it demonstrates cytokinin-like effects, activating AHK3 and AHK4/CRE1 receptors in Arabidopsis thaliana to stimulate beta-galactosidase activity, promoting callus growth in tobacco, betacyanin synthesis in Amaranthus cotyledons, and chlorophyll retention in wheat, comparable to 6-benzylaminopurine. It inhibits RECQ1 DNA helicase with a potency of 2818.4 nM and APE1 with a potency of 1122.0 nM. It acts as an agonist of the Thyroid Stimulating Hormone Receptor, affecting intracelular cAMP concentrations in Parental HEK 293 cells (19952.6 nM). Additionally, it inhibits PTHR (11220.2 nM) and shows effects on Anthrax Lethal Toxin Internalization (12589.3 nM). trans-Zeatin has antiviral properties, inhibiting SARS-CoV-2 induced cytotoxicity in Caco-2 and VERO-6 cells at 10 µM concentration with varying inhibition levels, and shows SARS-CoV-2 3CL-Pro protease inhibition with activity percentages up to 19.53% at 20 µM. The compound also exhibits inhibitory activity against human HDAC6 enzyme with low percentages of inhibition in enzymatic assays..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | trans-Zeatin ((E)-Zeatin) is the member of the plant growth hormone family known as cytokinins, which regulate cell division, development, and nutrient processing. |
| Synonyms | (E)-Zeatin |
| Molecular Weight | 219.24 |
| Formula | C10H13N5O |
| Cas No. | 1637-39-4 |
| Smiles | CC(CO)=CCNc1ncnc2[nH]cnc12 |
| Relative Density. | 1.40 g/cm3 (Predicted) |
| Storage | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 35.71 mg/mL (162.88 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
| In Vivo Formulation | 10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (4.56 mM), Sonication is recommended. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density. | ||||||||||||||||||||||||||||||||||||
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