Valencene [4630-07-3]
Referência NB-64-08154-100mg
Tamanho : 100mg
Marca : Neo Biotech
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Valencene
(Synonyms: NSC-148969, NSC148969, NSC 148969) Copy Product InfoSynonyms: NSC-148969, NSC148969, NSC 148969
Catalog No. T17214 Copy Product Info
Valencene (NSC-148969) is a sesquiterpenoid isolated from Cyperus rotundus and is an aroma component of citrus fruits and citrus-derived odors.ValenceneValencene has anti-allergic, anti-inflammatory, anti-melanogenic, and antioxidant activities. Valencene inhibits the overexpression of Th2 chemokines and pro-inflammatory chemokines by blocking the NF-κB pathway.
Cas No. 4630-07-3
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:93.00%
Appearance:Liquid
Color:White
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Product Information
Valencene AI Summary
Valencene shows bioactivity as an antagonist for TRPV1 and ORAI1 channels in HEK293T cells, leading to varying degrees of inhibition on capsaicin-induced currents. It inhibits store-operated calcium entry (SOCE) signaling in human Jurkat-T cells, resulting in reduced cytoplasmic calcium concentration. The compound also exhibits inhibitory effects on UV-induced melanogenesis in mouse B16F10 cells, reducing melanin levels. Moreover, it inhibits mushroom tyrosinase, which plays a role in melanin synthesis, as measured by spectrophotometry..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Valencene (NSC-148969) is a sesquiterpenoid isolated from Cyperus rotundus and is an aroma component of citrus fruits and citrus-derived odors.ValenceneValencene has anti-allergic, anti-inflammatory, anti-melanogenic, and antioxidant activities. Valencene inhibits the overexpression of Th2 chemokines and pro-inflammatory chemokines by blocking the NF-κB pathway. |
| Synonyms | NSC-148969, NSC148969, NSC 148969 |
| Molecular Weight | 204.35 |
| Formula | C15H24 |
| Cas No. | 4630-07-3 |
| Smiles | C[C@@H]1CCC=C2CC[C@H](C[C@@]12C)C(C)=C |
| Relative Density. | 0.89g/cm3 |
| Storage | Keep away from direct sunlight, Pure form: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 262.5 mg/mL (1284.56 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
| In Vivo Formulation | 10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (9.79 mM), Sonication is recommended. 10% DMSO+90% Saline: 10 mg/mL (48.94 mM), Suspension. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density. | ||||||||||||||||||||||||||||||||||||