Very Low Density Lipoprotein (VLDL), Human Plasma
Referência MBS173148-10mg
Tamanho : 10mg
Marca : MyBiosource
Very Low Density Lipoprotein (VLDL), Human Plasma
Very Low Density Lipoprotein (VLDL) Protein
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS173148MBS173148 is a protein targeting VLDL. Also known as Very Low Density Lipoprotein (VLDL), Human Plasma. Host: Human. More details
Product Overview
Product Name
Very Low Density Lipoprotein (VLDL), Protein
Full Product Name
Very Low Density Lipoprotein (VLDL), Human Plasma
Product Gene Name
VLDL protein
Product Synonym Names
Very Low Density Lipoprotein (VLDL)
Host
Human
Form/Format
Frozen liquid
Preparation and Storage
Ships in Dry Ice.
Store at -20 degree C (up to three months).
Store at -70 degree C (more than three months).
Avoid freeze-thaw cycles.
Store at -20 degree C (up to three months).
Store at -70 degree C (more than three months).
Avoid freeze-thaw cycles.
OMIM
gene 224050
Host Note
Fresh human plasma
Appearance
Yellow to orange liquid
Total Cholesterol
5,520 mg/dL (Enzymatic)
Triglyceride
14,200 mg/dL (Enzymatic)
Triglyceride Ratio
2.6 (Triglyceride/Total Cholesterol)
Handling
Handle as a potentially hazardous substance.
Thawing
Thaw quickly, in a 37 degree C water bath, removing as soon as thawed. Store at 2-8 degree C for up to one week, -20 degree C for up to three months, Long term at -70 degree C. Dilute with 0.15 M sodium chloride containing 0.01 mM EDTA.
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Product Categories/Family for VLDL protein
Other Notes
Small volumes of VLDL protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for VLDL. It may not necessarily be applicable to this product.
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
very low-density lipoprotein receptor isoform a
NCBI Official Synonym Full Names
very low density lipoprotein receptor
NCBI Official Symbol
VLDLR
NCBI Official Synonym Symbols
CARMQ1; CHRMQ1; VLDLRCH
UniProt Protein Name
Very low-density lipoprotein receptor
Protein Family
Very low-density lipoprotein receptor
UniProt Gene Name
VLDLR
UniProt Synonym Gene Names
VLDL receptor; VLDL-R
UniProt Entry Name
VLDLR_HUMAN
NCBI Protein Information
very low-density lipoprotein receptor; VLDL-R; VLDL receptor
NCBI Summary for VLDL
The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. This gene encodes a lipoprotein receptor that is a member of the LDLR family and plays important roles in VLDL-triglyceride metabolism and the reelin signaling pathway. Mutations in this gene cause VLDLR-associated cerebellar hypoplasia. Alternative splicing generates multiple transcript variants encoding distinct isoforms for this gene. [provided by RefSeq, Aug 2009]
Show more UniProt Comments for VLDL
VLDLR: Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation. Defects in VLDLR are the cause of cerebellar ataxia mental retardation and dysequilibrium syndrome type 1 (CMARQ1); also known as dysequilibrium syndrome (DES) or non- progressive cerebellar disorder with mental retardation. CMARQ1 is a congenital, non-progressive cerebellar ataxia associated with disturbed equilibrium, delayed ambulation, mental retardation and cerebellar hypoplasia. Additional features include short stature, strabismus, pes planus and, rarely, seizures. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Receptor, misc.
Chromosomal Location of Human Ortholog: 9p24
Cellular Component: membrane; integral to membrane; plasma membrane; coated pit; receptor complex
Molecular Function: very-low-density lipoprotein receptor activity; low-density lipoprotein receptor activity; very-low-density lipoprotein binding; protein binding; apolipoprotein binding; calcium ion binding; glycoprotein binding; calcium-dependent protein binding
Biological Process: cholesterol metabolic process; nervous system development; receptor-mediated endocytosis; positive regulation of protein kinase activity; ventral spinal cord development; negative regulation of transcription from RNA polymerase II promoter; lipid transport; signal transduction; memory
Disease: Cerebellar Ataxia, Mental Retardation, And Dysequilibrium Syndrome 1
Show more Protein type: Membrane protein, integral; Receptor, misc.
Chromosomal Location of Human Ortholog: 9p24
Cellular Component: membrane; integral to membrane; plasma membrane; coated pit; receptor complex
Molecular Function: very-low-density lipoprotein receptor activity; low-density lipoprotein receptor activity; very-low-density lipoprotein binding; protein binding; apolipoprotein binding; calcium ion binding; glycoprotein binding; calcium-dependent protein binding
Biological Process: cholesterol metabolic process; nervous system development; receptor-mediated endocytosis; positive regulation of protein kinase activity; ventral spinal cord development; negative regulation of transcription from RNA polymerase II promoter; lipid transport; signal transduction; memory
Disease: Cerebellar Ataxia, Mental Retardation, And Dysequilibrium Syndrome 1
Research Articles on VLDL
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with VLDL protein
| Reference Product | PubMed Publications |
|---|---|
| DAB1 protein | >69 publications with VLDL and DAB1 |
| APOE protein | >52 publications with VLDL and APOE |
| RELN protein | >19 publications with VLDL and RELN |
| SERPINE1 protein | >11 publications with VLDL and SERPINE1 |
| FYN protein | >11 publications with VLDL and FYN |
| PCSK9 protein | >9 publications with VLDL and PCSK9 |
| PAFAH1B1 protein | >6 publications with VLDL and PAFAH1B1 |
| LRPAP1 protein | >2 publications with VLDL and LRPAP1 |
| PLAU protein | >1 publications with VLDL and PLAU |
Pathways associated with VLDL protein
| Products by Pathway | Pathway Diagram |
|---|---|
| Lissencephaly Gene (LIS1) In Neuronal Migration And Development Pathway antibodies | Lissencephaly Gene (LIS1) In Neuronal Migration And Development Pathway Diagram |
| Reelin Signaling Pathway antibodies | Reelin Signaling Pathway Diagram |
Diseases associated with VLDL protein
| Disease Name | Pubmed Publications |
|---|---|
| Nervous System Diseases Antibodies | >44 publications with VLDL and Nervous System Diseases |
| Cardiovascular Diseases Antibodies | >27 publications with VLDL and Cardiovascular Diseases |
| Disease Models, Animal Antibodies | >19 publications with VLDL and Disease Models, Animal |
| Fatty Liver Antibodies | >12 publications with VLDL and Fatty Liver |
| Inflammation Antibodies | >11 publications with VLDL and Inflammation |
| Obesity Antibodies | >9 publications with VLDL and Obesity |
| Dysequilibrium syndrome Antibodies | >8 publications with VLDL and Dysequilibrium syndrome |
| Liver Diseases Antibodies | >8 publications with VLDL and Liver Diseases |
| Adenocarcinoma Antibodies | >6 publications with VLDL and Adenocarcinoma |
| Atrophy Antibodies | >6 publications with VLDL and Atrophy |
Organs/Tissues associated with VLDL protein
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Brain Antibodies | >124 publications with VLDL and Brain |
| Blood Antibodies | >58 publications with VLDL and Blood |
| Vascular Antibodies | >41 publications with VLDL and Vascular |
| Liver Antibodies | >38 publications with VLDL and Liver |
| Embryonic Tissue Antibodies | >35 publications with VLDL and Embryonic Tissue |
| Muscle Antibodies | >33 publications with VLDL and Muscle |
| Adipose Tissue Antibodies | >25 publications with VLDL and Adipose Tissue |
| Heart Antibodies | >25 publications with VLDL and Heart |
| Ovary Antibodies | >23 publications with VLDL and Ovary |
| Eye Antibodies | >19 publications with VLDL and Eye |