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> WAVE 1 (WASF1) Human siRNA Oligo Duplex (Locus ID 8936)

WAVE 1 (WASF1) Human siRNA Oligo Duplex (Locus ID 8936)

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Referência SR305910

Tamanho : 1kit


WAVE 1 (WASF1) Human siRNA Oligo Duplex (Locus ID 8936)

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SKU
SR305910
WASF1 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each
 

Other products for "WASF1 or NM_001024934"

Specifications
Product Data
Purity HPLC purified
Quality Control Tested by ESI-MS
Sequences Available with shipment
Components
WASF1 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 8936)
Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol
Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml
Stability One year from date of shipment when stored at -20°C.
Shipping Ambient
# of Transfections Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM).
Note Single siRNA duplex (10nmol) can be ordered.
Reference Data
RefSeq NM_001024934, NM_001024935, NM_001024936, NM_003931
UniProt ID Q92558
Synonyms NEDALVS; SCAR1; WAVE; WAVE1
Summary The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP)-family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott-Aldrich syndrome is a disease of the immune system, likely due to defects in regulation of actin cytoskeleton. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. provided by RefSeq, Jul 2008
Performance Guaranteed OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency.

For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at tech@clinisciences.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required).
Product Manuals
FAQs
  • siRNA
  • shRNA (HuSH-29)
SDS

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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Referência
Descrição
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Price Bef. VAT
SR30002
siRNA Related Product
 1nmol