| Short Description : | Rabbit polyclonal anti-Proto-oncogene FRAT1 (130-210 aa) for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
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| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 130-210 |
| Immunogen Region: | 130-210 aa |
| Specificity: | FRAT1 Polyclonal Antibody detects endogenous levels of protein. |
| Function | Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3. May play a role in tumor progression and collaborate with PIM1 and MYC in lymphomagenesis. |
| Protein Name | Proto-Oncogene Frat1Frequently Rearranged In Advanced T-Cell Lymphomas 1Frat-1 |
| Database Links | |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Proto-Oncogene Frat1 antibodyAnti-Frequently Rearranged In Advanced T-Cell Lymphomas 1 antibodyAnti-Frat-1 antibodyAnti-FRAT1 antibody |
Information sourced from Uniprot.org