CD7 Antibody

Referência OAEE00961

Tamanho : 100tests(T100)

Marca : Aviva Systems Biology


Datasheets/ManualsPrintable datasheet for CD7 Antibody
Product Info
Predicted Species ReactivityHuman
Product FormatStabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
ClonalityMonoclonal
CloneMEM-186
IsotypeIgG1
HostMouse
ConjugationPerCP
ApplicationFC
Reconstitution and Storage2°C to 8°C
ImmunogenHuman acute myelogenous leukaemia cell line KG-1.
PurificationPurified by size-exclusion chromatography
Concentration10 ul / test
SpecificityThe MEM-186 antibody reacts with CD7, a 40 kD type I transmembrane glycoprotein expressed on peripheral blood T lymphocytes, NK-cells, hematopoietic progenitors, monocytes (weakly) and also on acute lymphocytic leukemia.
HLDA VI; WS Code T 6T-015
FormulationPerCP
Storage BufferThe reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.
ReferenceLeukocyte Typing VI., Kishimoto T. et al. (Eds.), Garland Publishing Inc. (1997).
Nishimura M, Takanashi M, Okazaki H, Satake M, Nakajima K: Role of CD7 expressed in lung microvascular endothelial cells as Fc receptor for immunoglobulin M. Endothelium. 2006 Jul-Aug;13(4):287-92.
Chang H, Yeung J, Brandwein J, Yi QL: CD7 expression predicts poor disease free survival and post-remission survival in patients with acute myeloid leukemia and normal karyotype. Leuk Res. 2007 Feb;31(2):157-62. Epub 2006 Jul 11.
Lam GK, Liao HX, Xue Y, Alam SM, Scearce RM, Kaufman RE, Sempowski GD, Haynes BF. Expression of the CD7 ligand K-12 in human thymic epithelial cells: regulation byIFN-gamma. J Clin Immunol. 2005 Jan;25(1):41-9.
Alaibac M, Pigozzi B, Belloni-Fortina A, Michelotto A, Saponeri A, Peserico A. CD7 expression in reactive and malignant human skin T-lymphocytes. Anticancer Res. 2003 May-Jun;23(3B):2707-10.
Gene SymbolCD7
Gene Full NameCD7 molecule
Alias SymbolsCD7 antigen (p41), GP40, LEU-9, p41 protein, T-cell antigen CD7, T-cell leukemia antigen, T-cell surface antigen Leu-9, Tp40, TP41.
NCBI Gene Id924
Protein NameT-cell antigen CD7
Description of TargetNot yet known.
Uniprot IDP09564
Protein Accession #NP_006128.1
Nucleotide Accession #NM_006137.6