CD71/Transferrin receptor Polyclonal Antibody PE-Cy5 Conjugated

Referência MBS9462376-0,1mL

Tamanho : 0.1mL

Marca : MyBiosource


CD71 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9462376

MBS9462376 is an antibody targeting CD71. Also known as CD71/Transferrin receptor Polyclonal Antibody PE-Cy5 Conjugated. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

Product Overview

Online Datasheet in PDF
Product Name
CD71/Transferrin receptor, Polyclonal Antibody
Full Product Name
CD71/Transferrin receptor Polyclonal Antibody PE-Cy5 Conjugated
Product Gene Name
anti-CD71 antibody
Product Synonym Names
CD71/Transferrin receptor
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Purity/Purification
affinity purified by Protein A
Preparation and Storage
Store at -20 degree C for one year. Avoid repeated freeze/thaw cycles.
Shipped at 4 degree C.
Molecular Weight
84,871 Da
Chromosome Location
Chromosome: 3; NC_000003.11 (195776155..195809032, complement). Location: 3q29
OMIM
190010
3D Structure
ModBase 3D Structure for P02786
Conjugation
PE-Cy5
Immunogen Type
621-720/760

Product Categories/Family for anti-CD71 antibody

Conjugated Primary Antibodies
Applications Tested/Suitable for anti-CD71 antibody
Flow Cytometry (FC/FACS)
Application Notes for anti-CD71 antibody
FC/FACS: 1:50-200

Other Notes

Small volumes of anti-CD71 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CD71. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
transferrin receptor protein 1
NCBI Official Synonym Full Names
transferrin receptor (p90, CD71)
NCBI Official Symbol
TFRC
NCBI Official Synonym Symbols
T9; TR; TFR; p90; CD71; TFR1; TRFR
UniProt Protein Name
Transferrin receptor protein 1
UniProt Synonym Protein Names
T9; p90
UniProt Gene Name
TFRC
UniProt Synonym Gene Names
TR; TfR; TfR1; Trfr; sTfR
UniProt Entry Name
TFR1_HUMAN
NCBI Protein Information
transferrin receptor protein 1

UniProt Comments for CD71

TfR: the transferrin receptor. Regulates the cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied receptors into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system.

Protein type: Membrane protein, integral; Receptor, misc.; Cell surface

Chromosomal Location of Human Ortholog: 3q29

Cellular Component: extracellular space; cell surface; intracellular membrane-bound organelle; integral to plasma membrane; cytoplasmic membrane-bound vesicle; extracellular region; coated pit; recycling endosome; membrane; perinuclear region of cytoplasm; melanosome; plasma membrane; vesicle; endosome; external side of plasma membrane

Molecular Function: identical protein binding; protein binding; transferrin receptor activity; double-stranded RNA binding

Biological Process: receptor-mediated endocytosis; viral reproduction; cellular iron ion homeostasis; positive regulation of bone resorption; transferrin transport; osteoclast differentiation; regulation of cell growth; transmembrane transport; regulation of cell proliferation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CD71 antibody

 Reference Product  PubMed Publications
 HFE antibody  >18 publications with CD71 and HFE
 CD4 antibody  >1 publications with CD71 and CD4

Pathways associated with anti-CD71 antibody

 Products by Pathway  Pathway Diagram
 Clathrin Derived Vesicle Budding Pathway antibodies  Clathrin Derived Vesicle Budding Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 FOXA2 And FOXA3 Transcription Factor Networks Pathway antibodies  FOXA2 And FOXA3 Transcription Factor Networks Pathway Diagram
 Golgi Associated Vesicle Biogenesis Pathway antibodies  Golgi Associated Vesicle Biogenesis Pathway Diagram
 HIF-1 Signaling Pathway antibodies  HIF-1 Signaling Pathway Diagram
 HIF-1-alpha Transcription Factor Network Pathway antibodies  HIF-1-alpha Transcription Factor Network Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Iron Metabolism In Placenta Pathway antibodies  Iron Metabolism In Placenta Pathway Diagram

Diseases associated with anti-CD71 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >33 publications with CD71 and Neoplasms
 Iron Metabolism Disorders Antibodies  >28 publications with CD71 and Iron Metabolism Disorders
 Anemia Antibodies  >16 publications with CD71 and Anemia
 Disease Models, Animal Antibodies  >11 publications with CD71 and Disease Models, Animal
 Anemia, Iron-Deficiency Antibodies  >8 publications with CD71 and Anemia, Iron-Deficiency
 Lung Neoplasms Antibodies  >7 publications with CD71 and Lung Neoplasms
 Liver Diseases Antibodies  >6 publications with CD71 and Liver Diseases
 Brain Diseases Antibodies  >5 publications with CD71 and Brain Diseases
 Breast Neoplasms Antibodies  >4 publications with CD71 and Breast Neoplasms
 Drug Toxicity Antibodies  >4 publications with CD71 and Drug Toxicity

Organs/Tissues associated with anti-CD71 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >34 publications with CD71 and Blood
 Liver Antibodies  >22 publications with CD71 and Liver
 Brain Antibodies  >16 publications with CD71 and Brain
 Intestine Antibodies  >11 publications with CD71 and Intestine
 Lung Antibodies  >10 publications with CD71 and Lung
 Bone Antibodies  >8 publications with CD71 and Bone
 Skin Antibodies  >7 publications with CD71 and Skin
 Kidney Antibodies  >7 publications with CD71 and Kidney
 Embryonic Tissue Antibodies  >6 publications with CD71 and Embryonic Tissue
 Prostate Antibodies  >5 publications with CD71 and Prostate