D(1A) dopamine receptor
Referência MBS7042633-0,02mg
Tamanho : 0.02mg
Marca : MyBiosource
D(1a) Dopamine Receptor (DRD1) Recombinant Protein
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7042633This is a recombinant transmembrane protein expressed in a cell-free expression system. More details
Product Overview
Product Name
D(1A) dopamine receptor (DRD1), Recombinant Protein
Full Product Name
D(1A) dopamine receptor
Product Gene Name
DRD1 recombinant protein
Sequence
MRTLNTSAMD GTGLVVERDF SVRILTACFL SLLILSTLLG NTLVCAAVIR FRHLRSKVTN FFVISLAVSD LLVAVLVMPW KAVAEIAGFW PFGSFCNIWV AFDIMCSTAS ILNLCVISVD RYWAISSPFR YERKMTPKAA FILISVAWTL SVLISFIPVQ LSWHKAKPTS PSDGNATSLA ETIDNCDSSL SRTYAISSSV ISFYIPVAIM IVTYTRIYRI AQKQIRRIAA LERAAVHAKN CQTTTGNGKP VECSQPESSF KMSFKRETKV LKTLSVIMGV FVCCWLPFFI LNCILPFCGS GETQPFCIDS NTFDVFVWFG WANSSLNPII YAFNADFRKA FSTLLGCYRL CPATNNAIET VSINNNGAAM FSSHHEPRGS ISKECNLVYL IPHAVGSSED LKKEEAAGIA RPLEKLSPAL SVILDYDTDV SLEKIQPITQ NGQHPT
Host
Cell Free Expression
Form/Format
Liquid containing glycerol
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
Molecular Weight
49,293 Da
Sequence Positions
1-446. Full length.
OMIM
126449
Species
Homo sapiens (Human)
Product Categories/Family for DRD1 recombinant protein
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of DRD1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for DRD1 purchase
MBS7042633 is a recombinant protein targeting DRD1. Also known as D(1A) dopamine receptor. Host: Cell Free Expression.
Additional Details
NCBI/Uniprot data below describe general gene information for DRD1. It may not necessarily be applicable to this product.
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
D(1A) dopamine receptor
NCBI Official Synonym Full Names
dopamine receptor D1
NCBI Official Symbol
DRD1
NCBI Official Synonym Symbols
DADR; DRD1A
UniProt Protein Name
D(1A) dopamine receptor
UniProt Synonym Protein Names
Dopamine D1 receptor
Protein Family
D(1A) dopamine receptor
UniProt Gene Name
DRD1
UniProt Entry Name
DRD1_HUMAN
NCBI Protein Information
D(1A) dopamine receptor
NCBI Summary for DRD1
This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene. [provided by RefSeq, Jul 2008]
Show more UniProt Comments for DRD1
DRD1: a G-protein coupled receptor.One of the five types (D1 to D5) of receptors for dopamine. The most abundant dopamine receptor in the central nervous system. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Interacts with calcyon.
Protein type: Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1
Chromosomal Location of Human Ortholog: 5q35.1
Cellular Component: integral to plasma membrane; nonmotile primary cilium; plasma membrane
Molecular Function: dopamine binding; dopamine D1 receptor-like receptor activity; dopamine receptor activity; protein binding
Biological Process: adenylate cyclase activation; adult walking behavior; cerebral cortex GABAergic interneuron migration; dopamine metabolic process; dopamine receptor, adenylate cyclase activating pathway; dopamine receptor, phospholipase C activating pathway; elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); G-protein signaling, adenylate cyclase activating pathway; G-protein signaling, coupled to cyclic nucleotide second messenger; learning; mating behavior; positive regulation of cAMP biosynthetic process; positive regulation of cell migration; positive regulation of potassium ion transport; positive regulation of release of sequestered calcium ion into cytosol; positive regulation of synaptic transmission, glutamatergic; prepulse inhibition; regulation of dopamine uptake; response to drug; synaptic transmission, dopaminergic; synaptogenesis; transmission of nerve impulse; visual learning
Show more Protein type: Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1
Chromosomal Location of Human Ortholog: 5q35.1
Cellular Component: integral to plasma membrane; nonmotile primary cilium; plasma membrane
Molecular Function: dopamine binding; dopamine D1 receptor-like receptor activity; dopamine receptor activity; protein binding
Biological Process: adenylate cyclase activation; adult walking behavior; cerebral cortex GABAergic interneuron migration; dopamine metabolic process; dopamine receptor, adenylate cyclase activating pathway; dopamine receptor, phospholipase C activating pathway; elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); G-protein signaling, adenylate cyclase activating pathway; G-protein signaling, coupled to cyclic nucleotide second messenger; learning; mating behavior; positive regulation of cAMP biosynthetic process; positive regulation of cell migration; positive regulation of potassium ion transport; positive regulation of release of sequestered calcium ion into cytosol; positive regulation of synaptic transmission, glutamatergic; prepulse inhibition; regulation of dopamine uptake; response to drug; synaptic transmission, dopaminergic; synaptogenesis; transmission of nerve impulse; visual learning
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Pathways associated with DRD1 recombinant protein
| Products by Pathway | Pathway Diagram |
|---|---|
| Alcoholism Pathway antibodies | Alcoholism Pathway Diagram |
| Alcoholism Pathway antibodies | Alcoholism Pathway Diagram |
| Amine Ligand-binding Receptors Pathway antibodies | Amine Ligand-binding Receptors Pathway Diagram |
| Amphetamine Addiction Pathway antibodies | Amphetamine Addiction Pathway Diagram |
| Amphetamine Addiction Pathway antibodies | Amphetamine Addiction Pathway Diagram |
| Calcium Signaling Pathway antibodies | Calcium Signaling Pathway Diagram |
| Calcium Signaling Pathway antibodies | Calcium Signaling Pathway Diagram |
| Class A/1 (Rhodopsin-like Receptors) Pathway antibodies | Class A/1 (Rhodopsin-like Receptors) Pathway Diagram |
| Cocaine Addiction Pathway antibodies | Cocaine Addiction Pathway Diagram |
| Cocaine Addiction Pathway antibodies | Cocaine Addiction Pathway Diagram |
Diseases associated with DRD1 recombinant protein
| Disease Name | Pubmed Publications |
|---|---|
| Mental Disorders Antibodies | >123 publications with DRD1 and Mental Disorders |
| Schizophrenia Antibodies | >53 publications with DRD1 and Schizophrenia |
| Nervous System Diseases Antibodies | >43 publications with DRD1 and Nervous System Diseases |
| Brain Diseases Antibodies | >34 publications with DRD1 and Brain Diseases |
| Bipolar Disorder Antibodies | >23 publications with DRD1 and Bipolar Disorder |
| Movement Disorders Antibodies | >18 publications with DRD1 and Movement Disorders |
| Hypertension Antibodies | >15 publications with DRD1 and Hypertension |
| Depressive Disorder Antibodies | >13 publications with DRD1 and Depressive Disorder |
| Basal Ganglia Diseases Antibodies | >12 publications with DRD1 and Basal Ganglia Diseases |
| Anxiety Disorders Antibodies | >10 publications with DRD1 and Anxiety Disorders |
Organs/Tissues associated with DRD1 recombinant protein
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Brain Antibodies | >121 publications with DRD1 and Brain |
| Eye Antibodies | >3 publications with DRD1 and Eye |
| Pancreas Antibodies | >1 publications with DRD1 and Pancreas |