Orb1299430-1ml | Farnesol [4602-84-0] Clinisciences

Farnesol

SKU: orb1299430

Description

Farnesol is a naturally occurring sesquiterpene alcohol with documented antibacterial properties. It is widely used in microbiological research for in vitro studies of biofilm inhibition and as a chemical probe for investigating bacterial quorum-sensing mechanisms.

Research Area

Infectious Disease & Virology, Metabolism Research

Images & Validation

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Key Properties

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CAS Number	4602-84-0
MW	222.37
Purity	95.00% (May vary between batches)
Formula	C₁₅H₂₆O
SMILES	OCC=C(C)CCC=C(C)CCC=C(C)C
Target	Antibiotic,Antibacterial,Endogenous Metabolite
Solubility	DMSO:9 mg/mL (40.47 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (4.5 mM)

Bioactivity

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In Vivo	Farnesol, an acyclic sesquiterpene alcohol, is predominantly found in essential oils of various plants in nature, exhibit anti-cancer and anti-inflammatory effects, and also alleviate allergic asthma, gliosis, and edema. In numerous tumor cell lines, farnesol can modulate various tumorigenic proteins and/or modulates diverse signal transduction cascades. It can also induce apoptosis and downregulate cell proliferation, angiogenesis, and cell survival. To exert its anti-inflammatory/anti-oncogenic effects, farnesol can modulate Ras protein and nuclear factor kappa-light-chain-enhancer of activated B cells activation to downregulate the expression of various inflammatory mediators such as cyclooxygenase-2, inducible nitric oxide synthase, tumor necrosis factor alpha, and interleukin-6.

In Vivo

Farnesol, an acyclic sesquiterpene alcohol, is predominantly found in essential oils of various plants in nature, exhibit anti-cancer and anti-inflammatory effects, and also alleviate allergic asthma, gliosis, and edema. In numerous tumor cell lines, farnesol can modulate various tumorigenic proteins and/or modulates diverse signal transduction cascades. It can also induce apoptosis and downregulate cell proliferation, angiogenesis, and cell survival. To exert its anti-inflammatory/anti-oncogenic effects, farnesol can modulate Ras protein and nuclear factor kappa-light-chain-enhancer of activated B cells activation to downregulate the expression of various inflammatory mediators such as cyclooxygenase-2, inducible nitric oxide synthase, tumor necrosis factor alpha, and interleukin-6.

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Antibiotic, Bacterial, Inhibitor, Human Endogenous Metabolite, Endogenous Metabolite, EndogenousMetabolite, Farnesol, inhibit

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Human Farnesoid X Receptor (FXR) ELISA Kit [orb776627]
Reactivity:
Human
Dynamic Range:
0.16-10 ng/mL
Sensitivity:
0.066 ng/mL
Sizes Available: 48 T, 96 T
Rat Farnesoid X Receptor (FXR) ELISA Kit [orb780821]
Reactivity:
Rat
Dynamic Range:
0.16-10 ng/mL
Sensitivity:
0.051 ng/mL
Sizes Available: 48 T, 96 T
Mouse Farnesoid X Receptor (FXR) ELISA Kit [orb780182]
Reactivity:
Mouse
Dynamic Range:
0.16-10 ng/mL
Sensitivity:
0.051 ng/mL
Sizes Available: 48 T, 96 T