Human Glutamate receptor ionotropic, NMDA 2D (GRIN2D) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GRIN2D
Locus ID	2906
Kit Components	GA101962G1, Glutamate receptor ionotropic, NMDA 2D gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101962G2, Glutamate receptor ionotropic, NMDA 2D gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101962G3, Glutamate receptor ionotropic, NMDA 2D gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_000836
UniProt ID	O15399
Synonyms	EB11; GluN2D; NMDAR2D; NR2D
Summary	N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). [provided by RefSeq, Mar 2010]