CD8 APC
Catalog #
Size
Lymphocyte-gated human PBMCs stained with CD8 APC (RED); Lymphocyte-gated human PBMCs stained with RPC5.4 IgG2a APC (BLUE).
| Conjugation | APC |
|---|---|
| Antigen | CD8 |
| Clone | OKT8 |
| Isotype | IgG2a, k |
| Applications | FC |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Primary/Secondary | Primary |
| Immunogen | Human peripheral blood T lymphocytes |
| Format | 0.09% sodium azide, 0.2% BSA (w/v), PBS pH 7.2 |
| Storage | 2-8°C |
| Status | RUO |
| Excitation Laser | Red (633nm) |
Description:
Clone OKT8, a mouse monoclonal antibody, binds with a 32-34 kDa type I transmembrane glycoprotein known as CD8 a member of the immunoglobulin superfamily. OKT8 binds to CD8α, which forms either a homodimer or a heterodimer with CD8β. It is expressed on the surface of cytotoxic T cells, NK cells, cortical thymocytes, and on some dendritic cells. CD8 functions as a co-receptor for T-cell receptors and specifically binds to class I MHC for antigen recognition and T-cell activation.
Clone OKT8, a mouse monoclonal antibody, binds with a 32-34 kDa type I transmembrane glycoprotein known as CD8 a member of the immunoglobulin superfamily. OKT8 binds to CD8α, which forms either a homodimer or a heterodimer with CD8β. It is expressed on the surface of cytotoxic T cells, NK cells, cortical thymocytes, and on some dendritic cells. CD8 functions as a co-receptor for T-cell receptors and specifically binds to class I MHC for antigen recognition and T-cell activation.