USP6 probe for ISH CE/IVD - Sarcomas

USP6 probe for ISH CE/IVD - Sarcomas

 

Nodular fasciitis is a self-limited myofibroblastic lesion that can be misdiagnosed as a sarcoma as a result of its rapid growth, cellularity, and sometimes prominent mitotic activity. Nodular fasciitis (NF) is a common benign mesenchymal lesion that may progress through myxoid, cellular, and fibrous phases. The differential diagnosis of NF includes many other spindle cell neoplasms and it may be misdiagnosed as a sarcoma due to its rapid growth and active mitotic activity. Recently, it was discovered that the entire coding region of ubiquitin-specific peptidase 6 (USP6), an oncogene translocated in aneurysmal bone cyst (ABC), is fused to the MYH9 promoter region in up to 92% of NFs. This finding indicates a potential application of USP6 gene expression or gene break-apart as a biomarker of NF. However, the sensitivity and specificity of USP6 as a biomarker for nodular fasciitis is not known.

 

 

Resultado da sua pesquisa : 5 produto encontrado

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RUOCE / IVD
  • DIG-DNP 1
  • Green-Orange 1
  • Probe
  • ISH 4
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Referência
Descrição
Cond.
Price Bef. VAT
C-3077-100
 0,1ml/10tests 
USP6BA-10-ORGR
 10Tests-20µl