Anti-Tyrosine Hydroxylase Antibody (6W97)
Referência NB-64-119521-100uL
Tamanho : 100uL
Marca : Neo Biotech
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Anti-Tyrosine Hydroxylase Antibody (6W97)
(Synonyms: tyrosine hydroxylase) Copy Product InfoSynonyms: tyrosine hydroxylase
Catalog No. TMAC-04177 Copy Product Info
Anti-Tyrosine Hydroxylase Antibody (6W97) is a Rabbit antibody targeting Tyrosine Hydroxylase. Anti-Tyrosine Hydroxylase Antibody (6W97) can be used in FCM,ICC,IHC,WB.
For research use only—not for human use. No sales to individuals. Use as intended only.
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
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Stability & Storage
| Description | Anti-Tyrosine Hydroxylase Antibody (6W97) is a Rabbit antibody targeting Tyrosine Hydroxylase. Anti-Tyrosine Hydroxylase Antibody (6W97) can be used in FCM,ICC,IHC,WB. |
| Synonyms | tyrosine hydroxylase |
| Ig Type | IgG |
| Clone | 6W97 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of Tyrosine Hydroxylase on PC-12 cells lysates using anti-Tyrosine Hydroxylase antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-Tyrosine Hydroxylase antibody. Counter stained with hematoxylin. 3. ICC staining Tyrosine Hydroxylase in N2A cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 4. ICC staining Tyrosine Hydroxylase in NIH/3T3 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 5. ICC staining Tyrosine Hydroxylase in SH-SY-5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 6. Flow cytometric analysis of N2A cells with Tyrosine Hydroxylase antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as secondary antibody.  , , , , , |
| Application | FCM ICC IHC WB |
| Recommended Dose | WB: 1:1000-5000; IHC: 1:50-200; ICC: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The enzyme tyrosine hydroxylase (TH), also designated tyrosine 3-monooxygenase (TY3H), catalyzes the conversion of tyrosine to L-dopa, which is the rate limiting step in the biosynthesis of catecholamines such as dopamine, adrenalin and noradrenalin. TH is thought to play a role in the pathogenesis of Parkinson's disease, which is associated with reduced dopamine levels. Two transcription factor binding sites in the proximal region of the TH gene, the TPA-responsive element (TRE) and the c-AMP responsive element (CRE), have been implicated in the complex regulation of the TH gene. TH is also known to be upregulated by the glia maturation factor (GMF), a Cdc 10/SWI6 motif-containing protein called V-1, and a variety of additional compounds. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID | P07101 |
| Molecular Weight | Theoretical: 58 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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