Antiviral agent 62

Antiviral agent 62 (Compound 16 h) is an orally active antiviral agent that inhibits the activity of HIV with an IC₅₀ value of 8 nM against HIV (MJ4)^[1].

IC50: 8 nM (HIV (MJ4))^[1].

628.85

C₃₀H₅₇N₆O₄PS

C[C@@H](OCP(OCCCSCCCCCCCCCCCCC1CCCCC1)([O-])=O)CN2C=NC3=C(N)N=CN=C23.[NH4+]

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. D’Erasmo M P, et al. Building Metabolically Stable and Potent Anti-HIV Thioether-Lipid Analogues of Tenofovir Exalidex: A thorough Pharmacological Analysis[J]. Journal of Medicinal Chemistry, 2024.  [Content Brief]