GA105883G1, HDAC3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa
GA105883G2, HDAC3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa
GA105883G3, HDAC3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa
1 CRISPRa-Enhancer vector, SKU GE100056
1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer
These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. provided by RefSeq, Jul 2008
HDAC3 - human gene knockout kit via CRISPR, HDR mediated
1 kit
KN200605BN
HDAC3 - human gene knockout kit via CRISPR, HDR mediated
1 kit
KN200605LP
HDAC3 - human gene knockout kit via CRISPR, HDR mediated
1 kit
KN200605RB
HDAC3 - human gene knockout kit via CRISPR, HDR mediated
1 kit
KN400605
HDAC3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
1 kit
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
