IL13 (Human) ELISpot Kit

Quantification

Entrez GeneID

Gene Name

IL13

Gene Alias

ALRH, BHR1, IL-13, MGC116786, MGC116788, MGC116789, P600

Gene Description

interleukin 13

Omim ID

Gene Ontology

Gene Summary

This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq

Other Designations

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