Recombinant Human FSH

Referência DCM28-500ug

Tamanho : 500ug

Marca : Novoprotein


Description
Recombinant Human Follicle-Stimulating Hormone α/β Dimer is produced by Mammalian expression system and the target gene is expressed with a Flag tag&6His at the C-terminus.
Accession
P01215 &
P01225
Known As
Follicle-stimulating hormone; FSH; FSH alpha/beta
Mol Mass
10.2&12.5 kDa
APMol Mass
20-30 kDa, reducing conditions
Formulation Description
Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
Purity-SDS-PAGE
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Purity-SEC-HPLC
Greater than 95% as determined by SEC-HPLC.(QC verified)
Bioactivity Data
0
Storage
  • Reconstituted protein solution should be stored at ≤ -20°C.
  • Stable for at least 24 months when stored as instructed.
Shipping
The product is shipped on dry ice pack.Upon receipt, store it immediately at the temperature listed below.
Background
Human Follicle-stimulating hormone (FSH) is a member of glycoprotein hormones subunit beta family, whichalso includes LH, chorionic gonadotropin (CG) and thyroid-stimulating hormone (TSH). FSH and its familymembers are heterodimers consisting of non-covalently linked α- and β-subunits. They share an identical αsubunit, and β-subunits vary. FSH has a unique β-subunit (FSHβ), which confers its specific biologic activityand is responsible for interaction with the FSH-receptor which belongs to a subfamily of GPCRs calledleucine-rich-repeat-containing GPCRs (LGRs). FSH is secreted from the pituitary gland and regulatesreproduction in mammals. FSH stimulates sertoli cell proliferation in testes and supports spermatogenesis inmales, and induces the maturation of ovarian follicles in females.