Recombinant Human FSH

Referência MBS7621807-0,5mg

Tamanho : 0.5mg

Marca : MyBiosource


FSH Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7621807

MBS7621807 is a recombinant protein targeting FSH. Also known as Recombinant Human FSH. Host: Mammalian Cells. More details

Product Overview

Online Datasheet in PDF
Product Name
FSH, Recombinant Protein
Full Product Name
Recombinant Human FSH
Product Gene Name
FSH recombinant protein
Product Synonym Names
Follicle-stimulating hormone; FSH; FSH alpha/beta
Sequence
Ala25-Ser1 16&Asn19-G lu129
Host
Mammalian Cells
Form/Format
Lyophilized from a 0.2um filtered solution of PBS, pH7.4
Purity/Purification
Greater than 95% as determined by SDS-PAGE.
Preparation and Storage
The lyophilized protein is stable at -20 degree C for up to 1 year. After reconstitution, the protein solution is stable at -20 to -80 degree C for 3 months or 1 week at 2 to 8 degree C under sterile conditions. For extended storage, it is recommended to further dilute in working aliquots, avoid repeated freeze/thaw cycle.
Molecular Weight
13,075 Da
OMIM
118850
3D Structure
ModBase 3D Structure for P01215
Species
Human
Endotoxin
< 1 EU/ug as determined by LAL test.
Tag
C-terminal His-DYKDDDDK Tag
Reconstitution
Centrifuge the vial at 10000rpm for 30s before opening, reconstitute in sterile distilled water to a concentration of 0.1-1mg/ml by gently pipetting 2-3 times, don't vortex.

Product Categories/Family for FSH recombinant protein

cytokines
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for FSH recombinant protein
Western Blot (WB), ELISA (EIA)

Other Notes

Small volumes of FSH recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for FSH. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
thyroid-stimulating hormone alpha subunit
NCBI Official Synonym Full Names
glycoprotein hormones, alpha polypeptide
NCBI Official Symbol
CGA
NCBI Official Synonym Symbols
HCG; LHA; FSHA; GPHa; TSHA; GPHA1; CG-ALPHA
UniProt Protein Name
Glycoprotein hormones alpha chain
UniProt Synonym Protein Names
Anterior pituitary glycoprotein hormones common subunit alpha; Choriogonadotropin alpha chain; Chorionic gonadotrophin subunit alpha; CG-alpha; Follicle-stimulating hormone alpha chain; FSH-alpha; Follitropin alpha chain; Luteinizing hormone alpha chain; LSH-alpha; Lutropin alpha chain; Thyroid-stimulating hormone alpha chain; TSH-alpha; Thyrotropin alpha chain
Protein Family
Follitropin
UniProt Gene Name
CGA
UniProt Synonym Gene Names
CG-alpha; FSH-alpha; LSH-alpha; TSH-alpha
UniProt Entry Name
GLHA_HUMAN
NCBI Protein Information
glycoprotein hormones alpha chain; FSH-alpha; LSH-alpha; TSH-alpha; lutropin alpha chain; follitropin alpha chain; thyrotropin alpha chain; choriogonadotropin alpha chain; luteinizing hormone alpha chain; chorionic gonadotrophin subunit alpha; thyroid-sti

NCBI Summary for FSH

The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
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UniProt Comments for FSH

CGA: The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 6q12-q21

Cellular Component: extracellular region

Molecular Function: protein binding; hormone activity

Biological Process: cellular protein metabolic process; cell-cell signaling; peptide hormone processing; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; signal transduction; positive regulation of cell migration
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with FSH recombinant protein

 Reference Product  PubMed Publications
 LHB recombinant protein  >28 publications with FSH and LHB
 FSHB recombinant protein  >27 publications with FSH and FSHB
 FSHR recombinant protein  >6 publications with FSH and FSHR
 TSHB recombinant protein  >3 publications with FSH and TSHB
 LHCGR recombinant protein  >2 publications with FSH and LHCGR
 CGB8 recombinant protein  >1 publications with FSH and CGB8

Pathways associated with FSH recombinant protein

 Products by Pathway  Pathway Diagram
 Amine-derived Hormones Pathway antibodies  Amine-derived Hormones Pathway Diagram
 Androgen Biosynthesis Pathway antibodies  Androgen Biosynthesis Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 FSH Signaling Pathway antibodies  FSH Signaling Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Glucocorticoid Receptor Regulatory Network Pathway antibodies  Glucocorticoid Receptor Regulatory Network Pathway Diagram

Diseases associated with FSH recombinant protein

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >872 publications with FSH and Neoplasms
 Adenocarcinoma Antibodies  >267 publications with FSH and Adenocarcinoma
 Nervous System Diseases Antibodies  >164 publications with FSH and Nervous System Diseases
 Prostatic Diseases Antibodies  >130 publications with FSH and Prostatic Diseases
 Prostatic Neoplasms Antibodies  >129 publications with FSH and Prostatic Neoplasms
 Lung Neoplasms Antibodies  >112 publications with FSH and Lung Neoplasms
 Brain Diseases Antibodies  >111 publications with FSH and Brain Diseases
 Cardiovascular Diseases Antibodies  >102 publications with FSH and Cardiovascular Diseases
 Disease Progression Antibodies  >93 publications with FSH and Disease Progression
 Hyperplasia Antibodies  >76 publications with FSH and Hyperplasia

Organs/Tissues associated with FSH recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >165 publications with FSH and Brain
 Lung Antibodies  >159 publications with FSH and Lung
 Stomach Antibodies  >131 publications with FSH and Stomach
 Liver Antibodies  >128 publications with FSH and Liver
 Thyroid Antibodies  >102 publications with FSH and Thyroid
 Heart Antibodies  >99 publications with FSH and Heart
 Muscle Antibodies  >97 publications with FSH and Muscle
 Vascular Antibodies  >92 publications with FSH and Vascular
 Pituitary Gland Antibodies  >71 publications with FSH and Pituitary Gland
 Skin Antibodies  >55 publications with FSH and Skin