SOD (Cu/Zn) antibody

Referência orb151415-100ug

Tamanho : 100ug

Marca : Biorbyt

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    SOD (Cu/Zn) antibody

    SOD (Cu/Zn) antibody

    Catalog Number: orb151415

    Catalog Numberorb151415
    CategoryAntibodies
    DescriptionRabbit polyclonal to SOD (PerCP). Superoxide dismutase (SOD) is an endogenously produced intracellular enzyme present in almost every cell in the body. It works by catalyzing the dismutation of the superoxide radical O2 to O2 and H2O2, which are then metabolized to H2O and O2 by catalase and glutathione peroxidase (2,5). In general, SODs play a major role in antioxidant defense mechanisms. There are two main types of SOD in mammalian cells. One form (SOD1) contains Cu and Zn ions as a homodimer and exists in the cytoplasm. The two subunits of 16 kDa each are linked by two cysteines forming an intra-subunit disulphide bridge. The second form (SOD2) is a manganese containing enzyme and resides in the mitochondrial matrix. It is a homotetramer of 80 kDa. The third form (SOD3 or EC-SOD) is like SOD1 in that it contains Cu and Zn ions, however it is distinct in that it is a homotetramer, with a mass of 30 kDA and it exists only in the extra-cellular space. SOD3 can also be distinguished by its heparin-binding capacity..
    Species/HostRabbit
    ClonalityPolyclonal
    Tested applicationsELISA, ICC, IHC, IP, WB
    ReactivityBovine, Fungi, Human, Mouse, Rat
    ImmunogenSynthetic Rat Cu/Zn SOD Peptide
    Concentration1 mg/ml
    Dilution rangeWB (1:2000), ICC/IF (1:120)
    ConjugationPerCP
    MW19kDa
    TargetSOD1
    Entrez24786
    UniProt IDP07632
    NCBINP_058746.1
    StorageConjugated antibodies should be stored at 4°C
    Buffer/PreservativesPBS pH 7.0, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
    Alternative namesSuperoxide dismutase1 antibody, ALS1 antibody, IPO
    NoteFor research use only
    Application notes0.5 µg/ml of SPC-115 was sufficient for detection of Cu/Zn SOD in 20 µg of rat brain tissue extract by colorimetric immunoblot analysis using Goat anti-rabbit IgG:AP as the secondary antibody.
    Expiration Date12 months from date of receipt.