Thrombospondin antibody [A6-1]
Referência GTX21823-250ul
Tamanho : 250ul
Marca : Genetex
3
Host | Mouse |
---|---|
Clonality | Monoclonal |
Clone Name | A6-1 |
Isotype | IgG1 |
Application | WB, IHC-P, Neutralizing/Inhibition |
Reactivity | Human, Mouse |
Package | 250 μl |
View product citations for antibody GTX21823 on CiteAb
APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application | Recommended Dilution |
---|---|
WB | Assay dependent |
IHC-P | 1:25‐1:50 |
Neutralizing/Inhibition | Assay dependent |
Note : IHC-PRecommendations for antigen retrieval : Citrate Buffer pH 6.0 at room temperature for 30 mins. |
Not tested in other applications.
Calculated MW
129 kDa. ( Note )
Product Note
This antibody is specific to 450 kDa (non-reduced) and 170 to 180 kD (reduced) form of thrombospondin.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
BALB/C mice were injected with reduced and alkylated purified human TSP (fully denatured) from the supernatant of thrombin-activated platelets.
Purification
Purified IgG
Conjugation
Unconjugated
RRID
AB_384698
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
thrombospondin 1 , THBS , THBS-1 , TSP , TSP-1 , TSP1
Cellular Localization
Secreted , Endoplasmic reticulum
Background
The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis. [provided by RefSeq, Jul 2008]
Database
DATA IMAGES
GTX21823 IHC-P ImageIHC-P analysis of human tonsil tissue using GTX21823 Thrombospondin antibody [A6.1]. |
Application Reference
X Wang et al. Adv Sci (Weinh) 2023; : e2301428 Single-Cell RNA Sequencing and Spatial Transcriptomics Reveal Pathogenesis of Meningeal Lymphatic Dysfunction after Experimental Subarachnoid Hemorrhage
Application : Neutralizing/Inhibition
Reactivity : Mouse
Chu YY et al. Mol Neurobiol 2015; (Epub) Astrocytic CCAAT/Enhancer Binding Protein δ Regulates Neuronal Viability and Spatial Learning Ability via miR-135a.
Application : WB
Reactivity : Human
Clone Reference
Dixit VM et al. J Biol Chem. 1986; 261 (4):22859 Monoclonal antibodies that recognize calcium-dependent structures of human thrombospondin. Characterization and mapping of their epitopes.
Application : WB, Neutralizing/Inhibition
REVIEW
Thrombospondin antibody [A6-1] Cat. No. GTX21823
Rating | | ( Average 5 based on 3 users reviews) |
Western Blot(WB) | | ( Average 5 based on 3 users reviews) |
Application Reference
X Wang et al. Adv Sci (Weinh) 2023;:e2301428 Single-Cell RNA Sequencing and Spatial Transcriptomics Reveal Pathogenesis of Meningeal Lymphatic Dysfunction after Experimental Subarachnoid Hemorrhage
Application : Neutralizing/Inhibition
Reactivity : Mouse
Chu YY et al. Mol Neurobiol 2015; (Epub) Astrocytic CCAAT/Enhancer Binding Protein δ Regulates Neuronal Viability and Spatial Learning Ability via miR-135a.
Application : WB
Reactivity : Human
Clone Reference
Dixit VM et al. J Biol Chem. 1986; 261 (4):22859 Monoclonal antibodies that recognize calcium-dependent structures of human thrombospondin. Characterization and mapping of their epitopes.
Application : WB, Neutralizing/Inhibition
SDS | |
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PBS.pdf | |
Sodium Azide.pdf |