Custom service : Peptide synthesis

Custom service : Peptide synthesis

Peptides are used for a wide range of applications, from polyclonal antibody production to development of therapeutic molecules

Custom peptide production service offers the synthesis and purification of peptides. This peptide synthesis can be accompanied by modifications at the N or C terminal positions.

The peptide synthesis service adapts to your request:

  • Simple linear peptides
  • Complex peptides; cyclic,
  • Long chain peptides (up to 112 amino acids)
  • Modified amino acid containing peptides
  • Various grades of purity: crude, desalted, >75%、>85%、>90%、>95%、>98%.

Choose the purity of your peptide according to your needs:

Crude (>50 >70%)

  • High-throughput screening of lead compounds.
  • Mutation screening
  • Sequence optimization

Immuno-grade purity (>75%)

  • ELISA testing
  • Peptide arrays
  • Production, purification and testing of antibodies used in immunoassays

Biochemistry grade ( >85%)

  • For in-vitro bioassays and semi-quantitative applications (non-quantitative) such as studies in enzymology, epitope mapping, biological activity, enzyme-substrate interactions, or phosphorylation, as well as for peptide blocking studies for Western Blot and cell attachment.
  • Antigens for polyclonal antibody production
  • Coupling to chromatography resins for affinity purifications

High purity: >90% to >98%

  • Production of monoclonal antibodies
  • In vitro quantitative studies such as receptor-ligand interaction studies, enzyme-substrate and other biological activity studies, phosphorylation and proteolysis studies
  • Quantitative blocking and competitive inhibition assays, electrophoresis markers and chromatography standards
  • Quantitative bioassays (ELISA and RIA)
  • In vivo studies

Extremely high purity: >98%

  • In vivo studies, clinical trials, drug studies that use peptides as pharmaceuticals and cosmetic peptides for cosmeceuticals industry
  • Structure-activity relationship studies (enzyme-substrate studies, receptor-ligand interaction studies…)
  • Protein structure studies by nuclear magnetic resonance or protein crystallography.

The average time to synthesize a peptide is 2 to 3 weeks.

The peptide is analyzed by mass spectrometry, HPLC and is delivered with a synthesis report.

Peptides may have the following modifications (non-exhaustive list) :

  • In N-terminal
  • In C terminal
  • Non-usual amino acids
  • Conjugation