(Z)-Guggulsterone [39025-23-5]
Katalog-Nummer T17280-5mg
Size : 5mg
Marke : TargetMol
(Z)-Guggulsterone
Copy Product Info
(Z)-Guggulsterone inhibits the growth of human prostate cancer cells by causing apoptosis. Z-guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis.
Cas No. 39025-23-5
For research use only—not for human use. No sales to individuals. Use as intended only.
Select Batch
Purity:99.72%
Color:White
COA HNMR HPLC
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | (Z)-Guggulsterone inhibits the growth of human prostate cancer cells by causing apoptosis. Z-guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis. |
| In vitro | In HUVEC, Z-guggulsterone (10, 20 μM; 24 or 48 hours) induces a reduction in the level of VEGF-R2 protein [1]. |
| In vivo | In tumor volume and wet tumor weight, Z-guggulsterone (p.o.; 1 mg; 5 times/week) causes a statistically significant reduction [1]. |
| Molecular Weight | 312.45 |
| Formula | C21H28O2 |
| Cas No. | 39025-23-5 |
| Smiles | C\C=C1/C(=O)C[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C |
| Relative Density. | 1.10 g/cm3 (Predicted) |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO: < 1 mg/mL (insoluble or slightly soluble)  |