Specifications

Product Data
Species	Human
Expression Host	Sf9
Expression cDNA Clone or AA Sequence	Protein Sequence A DNA sequence from TrueORF clone, RC201111, encoding human full-length CTTN
Tag	C-DDK
Predicted MW	57.3 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	50 mM Tris-HCl, 100 mM glycine, pH 8.0, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping	Dry Ice
Reference Data
RefSeq	NP_612632
Locus ID	2017
UniProt ID	Q14247
Cytogenetics	11q13.3
RefSeq Size	3208
RefSeq ORF	1539
Synonyms	EMS1
Summary	This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. provided by RefSeq, May 2010
Protein Categories	Intracellular Proteins
Protein Families	Druggable Genome
Protein Pathways	Pathogenic Escherichia coli infection, Tight junction

FAQs

Protein FAQs

SDS

SDS for TP710315

Recombinant Protein Resources

Video tutorial: Why protein expression host matters Webinar Video: Overexpression lysate as positive controls for Western blot Product Overview Video: Overexpression lysates as positive controls for Western blot Video Tutorial: Knockout(KO) lysate and antibody specificity Product Brochure: Protein

SKU	Description	Size
PH301111	CTTN MS Standard C13 and N15-labeled recombinant protein (NP_612632)	10 ug
LC403359	Lyophilized CTTN HEK293T cell transient overexpression lysate (as WB positive control)	20 ug
LC417430	Lyophilized CTTN HEK293T cell transient overexpression lysate (as WB positive control)	20 ug
LC429248	Lyophilized CTTN HEK293T cell transient overexpression lysate (as WB positive control)	20 ug
LY403359	Transient overexpression lysate of cortactin (CTTN), transcript variant 2 (as WB positive control)	100 ug
LY417430	Transient overexpression lysate of cortactin (CTTN), transcript variant 1 (as WB positive control)	100 ug
LY429248	Transient overexpression lysate of cortactin (CTTN), transcript variant 1 (as WB positive control)	100 ug
TP301111	Recombinant protein of human cortactin (CTTN), transcript variant 2, 20 µg	20 ug