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> L-4FPG [19883-57-9]

L-4FPG [19883-57-9]

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Katalog-Nummer NB-64-10717-1g

Size : 1g

Marke : Neo Biotech


L-4FPG (Synonyms: L4FPG, L 4FPG)

Catalog No. T21102 Copy Product Info
Purity: 99.26%
L-4FPG is a Glycine derivative, inhibits the neutral amino acid transporters ASCT1 and ASCT2.

L-4FPG

Copy Product Info
Synonyms L4FPG, L 4FPG

L-4FPG is a Glycine derivative, inhibits the neutral amino acid transporters ASCT1 and ASCT2.

L-4FPG
Cas No. 19883-57-9

Batch Information
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Purity:99.26%
Appearance:Solid
Color:White
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COA HPLC

Product Introduction
L-4FPG AI Summary
L-4FPG exhibits bioactivities related to the inhibition of various serine transporters. It shows potent inhibition of D-serine transporter in rat visual cortex and ASCT2-mediated L-serine uptake in both rat hippocampal astrocytes and human HEK cells. Additionally, it inhibits ASCT1-mediated L-serine uptake in HEK cells and ASCT2-mediated D-serine uptake in rat hippocampal astrocytes. The compound also inhibits asc-1-mediated D-serine uptake in rat forebrain synaptosomes. The IC50 values indicate high potency of inhibition in the nanomolar range, with significant inhibition percentages observed at specific concentrations..
Note: Summary generated by AI. Data source: ChEMBL
Bioactivity
Description
L-4FPG is a Glycine derivative, inhibits the neutral amino acid transporters ASCT1 and ASCT2.
SynonymsL4FPG, L 4FPG
Chemical Properties
Molecular Weight169.15
FormulaC8H8FNO2
Cas No.19883-57-9
SmilesN[C@H](C(O)=O)c1ccc(F)cc1
Relative Density.1.31g/cm3
SequenceH-Phg(4-F)-OH
Sequence ShortX
Storage & Solubility Information
StorageShipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 0.85 mg/mL (5.03 mM), Sonication is recommended.
H2O: 0.98 mg/mL (5.79 mM), Sonication is recommended.
0.01 M HCl: 8.47 mg/mL (50.07 mM), Sonication is recommended.
Solution Preparation Table
DMSO/H2O/0.01 M HCl
1mg5mg10mg50mg
1 mM5.9119 mL29.5596 mL59.1191 mL295.5956 mL
5 mM1.1824 mL5.9119 mL11.8238 mL59.1191 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.