L-4FPG [19883-57-9]
Cat# NB-64-10717-1g
Size : 1g
Marca : Neo Biotech
L-4FPG (Synonyms: L4FPG, L 4FPG)
Catalog No. T21102 Copy Product Info
Purity: 99.26%
L-4FPG is a Glycine derivative, inhibits the neutral amino acid transporters ASCT1 and ASCT2.
L-4FPG
Copy Product InfoSynonyms L4FPG, L 4FPG
L-4FPG is a Glycine derivative, inhibits the neutral amino acid transporters ASCT1 and ASCT2.
Cas No. 19883-57-9
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Purity:99.26%
Appearance:Solid
Color:White
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Product Introduction
L-4FPG AI Summary
L-4FPG exhibits bioactivities related to the inhibition of various serine transporters. It shows potent inhibition of D-serine transporter in rat visual cortex and ASCT2-mediated L-serine uptake in both rat hippocampal astrocytes and human HEK cells. Additionally, it inhibits ASCT1-mediated L-serine uptake in HEK cells and ASCT2-mediated D-serine uptake in rat hippocampal astrocytes. The compound also inhibits asc-1-mediated D-serine uptake in rat forebrain synaptosomes. The IC50 values indicate high potency of inhibition in the nanomolar range, with significant inhibition percentages observed at specific concentrations..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | L-4FPG is a Glycine derivative, inhibits the neutral amino acid transporters ASCT1 and ASCT2. |
| Synonyms | L4FPG, L 4FPG |
| Molecular Weight | 169.15 |
| Formula | C8H8FNO2 |
| Cas No. | 19883-57-9 |
| Smiles | N[C@H](C(O)=O)c1ccc(F)cc1 |
| Relative Density. | 1.31g/cm3 |
| Sequence | H-Phg(4-F)-OH |
| Sequence Short | X |
| Storage | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||
| Solubility Information | DMSO: 0.85 mg/mL (5.03 mM), Sonication is recommended.  H2O: 0.98 mg/mL (5.79 mM), Sonication is recommended. 0.01 M HCl: 8.47 mg/mL (50.07 mM), Sonication is recommended. | |||||||||||||||
Solution Preparation Table | ||||||||||||||||
DMSO/H2O/0.01 M HCl
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density. | ||||||||||||||||