(-)-α-Terpineol [10482-56-1]
Katalog-Nummer NB-64-41651-1mL
Size : 1mLx10mM(inDMSO)
Marke : Neo Biotech
(-)-α-Terpineol (Synonyms: α-Terpineol)
Catalog No. T7468 Copy Product Info
Purity: 99.85%
(-)-α-Terpineol has antitumour, anti-inflammatory, and antimicrobial activities, it inhibits the growth of tumour cells through a mechanism that involves inhibition of the NF-kappaB pathway
(-)-α-Terpineol
Copy Product InfoSynonyms α-Terpineol
(-)-α-Terpineol has antitumour, anti-inflammatory, and antimicrobial activities, it inhibits the growth of tumour cells through a mechanism that involves inhibition of the NF-kappaB pathway
Cas No. 10482-56-1
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Purity:99.85%
Appearance:Solid
Color:White
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Product Introduction
(-)-α-Terpineol AI Summary
(-)-α-Terpineol exhibits a variety of biological activities across different systems. It has cicatrizant activity in mice, showing wound healing properties with an effective dose (ED50) of 240.0 mg/kg as measured by tensile strength. Additionally, it inhibits growth of mouse 3T3 cells with a GI50 of 17.0 ug/mL. It has antioxidant properties, with a DPPH radical scavenging EC50 value of 146.3 ug/mL, indicating its potential to neutralize free radicals. The compound demonstrates antimicrobial activity against a range of microorganisms, including Propionibacterium acnes, Streptococcus mutans, and Pityrosporum ovale, with MICs of 100.0, 400.0, and 400.0 ug/mL, respectively, as well as antifungal activity against Aspergillus flavus with complete inhibition at 60 uL and 20 uL concentrations. In terms of acaricidal activity, (-)-α-Terpineol is highly effective against Psoroptes cuniculi, exhibiting activity levels from 73.3% to 100.0% in various assays. It also shows insecticidal capabilities against Leptinotarsa decemlineata (Colorado potato beetle) and Musca domestica (house fly), with varying mortality rates and an LD50 of 137.5 ug for house flies. Furthermore, it exhibits anti-mite activity against Tetranychus urticae with LC50 values ranging from 36.1 to 44.2 microg/cm3. In specific enzymatic assays, (-)-α-Terpineol shows activity related to UGT1A4 but not UGT1A1, with an activity rate of 25.0 pm/min/mg. It also possesses a log K value of 0.82, suggesting a balance between hydrophobic and hydrophilic properties. This broad-spectrum bioactivity makes (-)-α-Terpineol a compound of interest for multiple applications including wound healing, antioxidation, antimicrobial, acaricidal, and insecticidal potential..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | (-)-α-Terpineol has antitumour, anti-inflammatory, and antimicrobial activities, it inhibits the growth of tumour cells through a mechanism that involves inhibition of the NF-kappaB pathway |
| Synonyms | α-Terpineol |
| Molecular Weight | 154.25 |
| Formula | C10H18O |
| Cas No. | 10482-56-1 |
| Smiles | CC1=CC[C@H](CC1)C(C)(C)O |
| Relative Density. | 0.93 g/cm3 |
| Storage | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 22.5 mg/mL (145.87 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
| In Vivo Formulation | 10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (12.97 mM), Sonication is recommended. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density. | ||||||||||||||||||||||||||||||||||||