Protein / Peptide

Protein / Peptide

Custom Service : Chemical Protein Synthesis
Proteins synthesized chemically of very high quality and purity

Custom Service : Protein analytics
We offer a range of analytical methods utilizing multiple assay platforms that be used to characterize a broad range of proteins expressed and purified by various methods.

Custom service : Peptide synthesis
Peptides are used for a wide range of applications, from polyclonal antibody production to development of therapeutic molecules  => Quote request

Custom service : Protein production and purification in a prokaryotic system
We propose a recombinant production in Escherichia Coli. => Quotation request

Custom service : Protein production and purification in an eukaryotic system
Use of an eukaryotic system allows to produce recombinant proteins that are submitted to post-traductional modifications, essentials to their functions. => Quotation request

Custom service : Protein production and purification in mammalian cells
Use of a mammalian model, in comparison with a primary eukaryotic model, allows to mimic more the post-traductional modifications of proteins, essentials to their functions. => Quotation request

Custom service : Protein production and purification in a human model
Use of a human model, in comparison with a mammalian model, allows to optimize the post-traductional modifications of proteins, essentials to their functions. => Quotation request

CUSTOM SERVICE : CHEMICAL PROTEIN SYNTHESIS

              Custom Chemical Protein Synthesis with absolute precision, very high purity and quality 


We offer Custom Chemical Protein Synthesis Service, using a chemical method that synthesises proteins amino acid by amino acid and making modifications on an atomic-scale.

By building custom proteins, atom by atom, we ensure localization of any modifications with absolute precision,

which can help you to design and create new therapeutic, vaccine and diagnostic mid-size proteins.

enlightenedYou encounter problems with the production of your proteins?

enlightenedYou need to produce a protein with specific modifications?

enlightenedYou want an optimal protein chemically synthesized in vitro?

 

► We can produce  mid-size proteins containing 70 to 400 amino acids to develop biopharmaceutical products

 

► We can produce not only native protein but also precisely modified proteins

 

► A large panel of modification are compatible with our skills and technologies

 

► Proteins have no isoforms, no endotoxins, no biological contaminants

 


 

We design the desired protein for our partners (Fusion, cyclic, glycosylated, specific modifications)
We synthesise amino acid by amino acid the protein
by our innovative and automated technology
We purify the protein many times during the synthesis stages
We proceed to a folding step to make a protein biologically active
 
      
Thanks to the evolving regulations and advanced technology, we can now think about biosimilar medications
 free of endotoxins and without other rDNA production contaminants impurities. 
 

ADVANTAGES

  • Protein with maximized biological activity
  • Complex proteins that cannot be produced by biological systems
  • Very high purity (Endotoxin-Free)
  • Bypass the problems with the proteins production (purity, inclusion bodies...))
  • Animal free
  • Homogeneity in Preparations
  • Need un-natural amino acids or finely controlled sidechains
  • Up to 400 AA (40 kD) long
  • Automated production at milligrams scale-up to Industrial scale

 

                                        
                                        
                                        

We work closely with our partners in designing, customising and optimising the proteins adapted to their project.expert in complex custom protein
synthesis by passing the limitations of classical recombinant methods.


Thanks to the evolving regulations and advanced technology, we can now think about biosimilar medications
 free of endotoxins and without other rDNA production contaminants impurities. 


Please contact us at tech@clinisciences.com for more information or for a quote request.