TNF alpha (TNF) Mouse Monoclonal Antibody [Clone ID: OTI1C1]

Cat# TA506513

Size : 100ul


TNF alpha (TNF) Mouse Monoclonal Antibody [Clone ID: OTI1C1]

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SKU
TA506513
TNF mouse monoclonal antibody, clone OTI1C1 (formerly 1C1)
 
Specifications
Product Data
Clone Name OTI1C1
Application ELISA (indirect), FC, IF, WB
Recommended Dilution WB 1:4000, IF 1:100
Reactivity Human
Antibody Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Full length human recombinant protein of human TNF(NP_000585) produced in HEK293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 25.5 kDa
Gene Name tumor necrosis factor
Database Link
Background This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. provided by RefSeq, Jul 2008
Synonyms DIF; TNF-alpha; TNFA; TNFSF2
Reference Data
Protein Categories ADC Targets, Allergies and autoimmune diseases, Chemokines, Cytokines, Growth Factors, Intracellular Proteins, Secreated Proteins
Protein Families Druggable Genome, Secreted Protein, Transcription Factors, Transmembrane
Protein Pathways Adipocytokine signaling pathway, Allograft rejection, Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Apoptosis, Asthma, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Fc epsilon RI signaling pathway, Graft-versus-host disease, Hematopoietic cell lineage, Hypertrophic cardiomyopathy (HCM), MAPK signaling pathway, Natural killer cell mediated cytotoxicity, NOD-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, Type I diabetes mellitus, Type II diabetes mellitus
SKU Description Size
CF506513 Carrier-free (BSA/glycerol-free) TNF mouse monoclonal antibody, clone OTI1C1 (formerly 1C1) 100 ug
TA506513AM TNF mouse monoclonal antibody,clone 1C1, Biotinylated 100 ul
TA506513BM TNF mouse monoclonal antibody,clone 1C1, HRP conjugated 100 ul
TA506513S TNF mouse monoclonal antibody, clone OTI1C1 (formerly 1C1) 30 ul

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