α2C adrenoceptor agonist 1 [928115-79-1]
Referentie T87683-50mg
Formaat : 50mg
Merk : TargetMol
α2C adrenoceptor agonist 1
α2C adrenoceptor agonist 1
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Cas No. 928115-79-1
With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Compound A (α2C adrenoceptor agonist 1) is an orally active, highly selective α2C-adrenoceptor agonist that does not penetrate the central nervous system. It exhibits EC50 and Ki values of 108 nM and 12 nM, respectively. This compound is utilized in research on nasal congestion [1]. |
| Targets&IC50 | α2C-adrenoceptor:108 nM (EC50), α2C-adrenoceptor:12 nM (Ki) |
| In vivo | Compound A, an α2C adrenoceptor agonist (5 mg/kg; p.o.), exhibits poor brain penetration in Sprague-Dawley rats, with its mean Cmax, Tmax, and area under the curve values being 0.8 μM, 0.7 hours, and 2 μM•h, respectively [1]. |
| Molecular Weight | 315.37 |
| Formula | C16H21N5O2 |
| Cas No. | 928115-79-1 |
| Smiles | C(N1C=2C(=CC=C(N(C(NC)=O)CC)C2)OCC1)C3=CN=CN3 |
| Storage | Shipping with blue ice. |