Kell blood group glycoprotein
Referentie MBS7042979-0,02mg
Formaat : 0.02mg
Merk : MyBiosource
Kell Blood Group Glycoprotein (KEL) Recombinant Protein
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7042979This is a recombinant transmembrane protein expressed in a cell-free expression system. More details
Product Overview
Online Datasheet in PDFProduct Name
Kell blood group glycoprotein, Recombinant Protein
Full Product Name
Kell blood group glycoprotein
Product Gene Name
KEL recombinant protein
Sequence
MEGGDQSEEE PRERSQAGGM GTLWSQESTP EERLPVEGSR PWAVARRVLT AILILGLLLC FSVLLFYNFQ NCGPRPCETS VCLDLRDHYL ASGNTSVAPC TDFFSFACGR AKETNNSFQE LATKNKNRLR RILEVQNSWH PGSGEEKAFQ FYNSCMDTLA IEAAGTGPLR QVIEELGGWR ISGKWTSLNF NRTLRLLMSQ YGHFPFFRAY LGPHPASPHT PVIQIDQPEF DVPLKQDQEQ KIYAQIFREY LTYLNQLGTL LGGDPSKVQE HSSLSISITS RLFQFLRPLE QRRAQGKLFQ MVTIDQLKEM APAIDWLSCL QATFTPMSLS PSQSLVVHDV EYLKNMSQLV EEMLLKQRDF LQSHMILGLV VTLSPALDSQ FQEARRKLSQ KLRELTEQPP MPARPRWMKC VEETGTFFEP TLAALFVREA FGPSTRSAAM KLFTAIRDAL ITRLRNLPWM NEETQNMAQD KVAQLQVEMG ASEWALKPEL ARQEYNDIQL GSSFLQSVLS CVRSLRARIV QSFLQPHPQH RWKVSPWDVN AYYSVSDHVV VFPAGLLQPP FFHPGYPRAV NFGAAGSIMA HELLHIFYQL LLPGGCLACD NHALQEAHLC LKRHYAAFPL PSRTSFNDSL TFLENAADVG GLAIALQAYS KRLLRHHGET VLPSLDLSPQ QIFFRSYAQV MCRKPSPQDS HDTHSPPHLR VHGPLSSTPA FARYFRCARG ALLNPSSRCQ LW
Host
Cell Free Expression
Form/Format
Liquid containing glycerol
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
Other Notes
Small volumes of KEL recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for KEL purchase
MBS7042979 is a recombinant protein targeting KEL. Also known as Kell blood group glycoprotein. Host: Cell Free Expression.
Additional Details
NCBI/Uniprot data below describe general gene information for KEL. It may not necessarily be applicable to this product.
NCBI Official Full Name
kell blood group glycoprotein
NCBI Official Synonym Full Names
Kell blood group, metallo-endopeptidase
NCBI Official Symbol
KEL
NCBI Official Synonym Symbols
ECE3; CD238
UniProt Protein Name
Kell blood group glycoprotein
UniProt Synonym Protein Names
CD_antigen: CD238
Protein Family
Kell blood group glycoprotein
UniProt Gene Name
KEL
UniProt Entry Name
KELL_HUMAN
NCBI Protein Information
kell blood group glycoprotein
NCBI Summary for KEL
This gene encodes a type II transmembrane glycoprotein that is the highly polymorphic Kell blood group antigen. The Kell glycoprotein links via a single disulfide bond to the XK membrane protein that carries the Kx antigen. The encoded protein contains sequence and structural similarity to members of the neprilysin (M13) family of zinc endopeptidases. [provided by RefSeq, Jul 2008]
Show more UniProt Comments for KEL
KEL: Zinc endopeptidase with endothelin-3-converting enzyme activity. Cleaves EDN1, EDN2 and EDN3, with a marked preference for EDN3. Belongs to the peptidase M13 family.
Protein type: EC 3.4.24.-; Protease; Membrane protein, integral
Chromosomal Location of Human Ortholog: 7q33
Cellular Component: integral to membrane; plasma membrane
Molecular Function: metalloendopeptidase activity; protein binding
Biological Process: vasoconstriction
Disease: Blood Group--kell System
Show more Protein type: EC 3.4.24.-; Protease; Membrane protein, integral
Chromosomal Location of Human Ortholog: 7q33
Cellular Component: integral to membrane; plasma membrane
Molecular Function: metalloendopeptidase activity; protein binding
Biological Process: vasoconstriction
Disease: Blood Group--kell System
Research Articles on KEL
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with KEL recombinant protein
| Reference Product | PubMed Publications |
|---|---|
| RHCE recombinant protein | >16 publications with KEL and RHCE |
| PIP recombinant protein | >6 publications with KEL and PIP |
| ITGA2 recombinant protein | >1 publications with KEL and ITGA2 |
Pathways associated with KEL recombinant protein
| Products by Pathway | Pathway Diagram |
|---|---|
| Class A/1 (Rhodopsin-like Receptors) Pathway antibodies | Class A/1 (Rhodopsin-like Receptors) Pathway Diagram |
| GPCR Ligand Binding Pathway antibodies | GPCR Ligand Binding Pathway Diagram |
| Peptide Ligand-binding Receptors Pathway antibodies | Peptide Ligand-binding Receptors Pathway Diagram |
| Signal Transduction Pathway antibodies | Signal Transduction Pathway Diagram |
| Signaling By GPCR Pathway antibodies | Signaling By GPCR Pathway Diagram |
Diseases associated with KEL recombinant protein
| Disease Name | Pubmed Publications |
|---|---|
| Male Urogenital Diseases Antibodies | >22 publications with KEL and Male Urogenital Diseases |
| Kidney Diseases Antibodies | >21 publications with KEL and Kidney Diseases |
| Anemia Antibodies | >18 publications with KEL and Anemia |
| Lung Diseases Antibodies | >17 publications with KEL and Lung Diseases |
| Liver Diseases Antibodies | >15 publications with KEL and Liver Diseases |
| Disease Models, Animal Antibodies | >14 publications with KEL and Disease Models, Animal |
| Neurologic Manifestations Antibodies | >13 publications with KEL and Neurologic Manifestations |
| Inflammation Antibodies | >10 publications with KEL and Inflammation |
| Hypertension Antibodies | >8 publications with KEL and Hypertension |
| Poisoning Antibodies | >6 publications with KEL and Poisoning |
Organs/Tissues associated with KEL recombinant protein
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Brain Antibodies | >25 publications with KEL and Brain |
| Lung Antibodies | >14 publications with KEL and Lung |
| Skin Antibodies | >14 publications with KEL and Skin |
| Spleen Antibodies | >10 publications with KEL and Spleen |
| Bone Marrow Antibodies | >8 publications with KEL and Bone Marrow |
| Ovary Antibodies | >7 publications with KEL and Ovary |
| Testis Antibodies | >5 publications with KEL and Testis |
| Embryonic Tissue Antibodies | >4 publications with KEL and Embryonic Tissue |
| Placenta Antibodies | >2 publications with KEL and Placenta |
| Uncharacterized Tissue Antibodies | >1 publications with KEL and Uncharacterized Tissue |


