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> Pepstatin A[26305-03-3]

Pepstatin A[26305-03-3]

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Referentie 10-1368-25mg

Formaat : 25mg

Merk : Focus Biomolecules


Pepstatin A | Aspartic protease inhibitor

CAS:
26305-03-3
Catalog Number:
10-1368
Activity:
Aspartic protease inhibitor
Chemical Name:
N-isovaleryl-L-valyl-L-valyl-3-hydroxy-6-methyl-γ-aminoheptanoyl-L-alanyl-3-hydroxy-6-methyl-γ-amino heptanoic acid
Molecular Weight:
685.90
Molecular Formula:
C34H63N5O9
Solubility:
Soluble in DMSO (up to 5 mg/ml) or in Ethanol (up to 1 mg/ml)
Physical Properties:
White solid
Purity:
98% by HPLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
Shipping Code:
RT

Available Options

Size :Quantity 
5 mg$32.00
25 mg$100.00
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This product is also available in the following library:
Protease Inhibitors

Pepstatin A (26305-03-3) is a selective inhibitor of aspartyl proteases.1 Inhibits human pepsin, human gastricsin, renin, cathepsin D and E and bovine chymosin.2 Does not inhibit thiol proteases, neutral proteases or serine proteases.3 Pepstatin A suppresses RANKL-induced osteoclast differentiation.4

References/Citations:

1) Merck Index 14:7147
2) Marciniszyn et al. (1976) Mode of inhibition of acid proteases by pepstatin; J. Biol. Chem., 251 7088
3) Oda (2012) New families of carboxy peptidases: serine-carboxyl peptidases and glutamic peptidases; J. Biochem., 151 13
4) Yoshida et al. (2006) Pepstatin A, an aspartic proteinase inhibitor, suppresses RANKL-induced osteoclast differentiation; J. Biochem., 139 583

26305-03-3, Aspartic protease inhibitor, Pepstatin A, Pepstatin A | Aspartic protease inhibitor
CAS:
26305-03-3
Catalog Number:
10-1368
Activity:
Aspartic protease inhibitor
Chemical Name:
N-isovaleryl-L-valyl-L-valyl-3-hydroxy-6-methyl-γ-aminoheptanoyl-L-alanyl-3-hydroxy-6-methyl-γ-amino heptanoic acid
Molecular Weight:
685.90
Molecular Formula:
C34H63N5O9
Solubility:
Soluble in DMSO (up to 5 mg/ml) or in Ethanol (up to 1 mg/ml)
Physical Properties:
White solid
Purity:
98% by HPLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
Shipping Code:
RT

Safety Data Sheet:

Download Safety Data Sheet

Product Data Sheet:

Download Product Data Sheet

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a restocking/refund fee

Pepstatin A (26305-03-3) is a selective inhibitor of aspartyl proteases.1 Inhibits human pepsin, human gastricsin, renin, cathepsin D and E and bovine chymosin.2 Does not inhibit thiol proteases, neutral proteases or serine proteases.3 Pepstatin A suppresses RANKL-induced osteoclast differentiation.4

References/Citations:

1) Merck Index 14:7147
2) Marciniszyn et al. (1976) Mode of inhibition of acid proteases by pepstatin; J. Biol. Chem., 251 7088
3) Oda (2012) New families of carboxy peptidases: serine-carboxyl peptidases and glutamic peptidases; J. Biochem., 151 13
4) Yoshida et al. (2006) Pepstatin A, an aspartic proteinase inhibitor, suppresses RANKL-induced osteoclast differentiation; J. Biochem., 139 583

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