Other Red DNA stains

Other Red DNA stains

Red DNA stains are vital tools in molecular biology, facilitating the visualization of DNA in various research applications. These stains are designed to selectively bind to DNA molecules, allowing researchers to observe and study genetic material under different imaging techniques. In live-cell imaging, red DNA stains play a crucial role in tracking DNA dynamics and structures within cells without causing significant harm or interference with cellular processes. Additionally, in techniques like agarose gel electrophoresis, red DNA stains are used to visualize DNA bands, aiding in the analysis of DNA fragments based on their size and migration patterns. The development of red DNA stains has significantly advanced molecular biology research by providing safer and more sensitive alternatives to traditional DNA dyes, enhancing the accuracy and efficiency of genetic studies.
Our product range offers a variety of options for nucleic acid gel staining, ranging from highly concentrated dyes to convenient kit formats. Whether you need a reliable solution for routine DNA staining or a specialized product for precise gel visualization, we have what you need.

In this category our dyes are designed to provide high sensitivity and excellent stability, ensuring consistent and reliable results with each use. Whether you're conducting routine analyses or advanced molecular biology research, our products are tailored to meet your needs.

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HY-K1007-500uL
 500uL 
orb385961-20ug
The retinoblastoma protein (protein name abbreviated pRb; gene name abbreviated RB or RB1) is a tumor suppressor protein that is dysfunctional in several major cancers. One function of pRb is to prevent excessive cell growth by inhibiting cell cycle progression until a cell is ready to divide. When the cell is ready to divide, pRb is phosphorylated, becomes inactive and allows cell cycle progression. It is also a recruiter of several chromatin remodeling enzymes such as methylases and acetylases.Rb restricts the cell's ability to replicate DNA by preventing its progression from the G1 (first gap phase) to S (synthesis phase) phase of the cell division cycle. Rb binds and inhibits transcription factors of the E2F family, which are composed of dimers of an E2F protein and a dimerization partner (DP) protein. The transcription activating complexes of E2 promoter-binding–protein-dimerization partners (E2F-DP) can push a cell into S phase. As long as E2F-DP is inactivated, the cell remains stalled in the G1 phase. When Rb is bound to E2F, the complex acts as a growth suppressor and prevents progression through the cell cycle. The Rb-E2F/DP complex also attracts a histone deacetylase (HDAC) protein to the chromatin, reducing transcription of S phase promoting factors, further suppressing DNA synthesis.[Wiki]mAb 1F8 ecognizes a 105kDa phosphoprotein, identified as retinoblastoma (Rb) gene product. It shows no cross reaction with p107 or p130. It specifically stains the nuclei of BT-20 cells and primary human foreskin fibroblast (HFF) cells. It does not stain the Rb-negative BT549 cells. It reacts with the hyperphosphorylated as well as the un (under) phosphorylated form of the Rb protein.
 20ug 
New
NB-03-0274
 500ul 
    1