Anti-N-SMase2 Antibody

Référence MBS8291535-0,1mL

Conditionnement : 0.1mL

Marque : MyBiosource


N-SMase2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8291535

MBS8291535 is an antibody targeting N-SMase2. Reactive in Human, Mouse, Rat. Host: Rabbit. Rabbit polyclonal antibody to N-SMase2 More details

Product Overview

Online Datasheet in PDF
Product Name
N-SMase2, Polyclonal Antibody
Full Product Name
Anti-N-SMase2 Antibody
Product Gene Name
anti-N-SMase2 antibody
Product Synonym Gene Name
SMPD3
Product Synonym Names
Sphingomyelin phosphodiesterase 3; Neutral sphingomyelinase 2; nSMase-2; nSMase2; Neutral sphingomyelinase II
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
Purified by immunogen affinity chromatography
Specificity
Recognizes endogenous levels of N-SMase2 protein.
Preparation and Storage
Upon receipt aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
OMIM
AJ250460 mRNA
3D Structure
ModBase 3D Structure for Q9NY59
Immunogen
Recombinant full length protein of human N-SMase2
Applications Tested/Suitable for anti-N-SMase2 antibody
Western Blot (WB)
Application Notes for anti-N-SMase2 antibody
WB: 1/500 - 1/2000

Western Blot (WB) of anti-N-SMase2 antibody

Western blot analysis of N-SMase2 expression in A549 (A), mouse brain (B), rat brain (C) whole cell lysates.
Rabbit Anti-N-SMase2 Polyclonal Antibody – Cat# MBS8291535

Other Notes

Small volumes of anti-N-SMase2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for N-SMase2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
sphingomyelin phosphodiesterase 3
NCBI Official Synonym Full Names
sphingomyelin phosphodiesterase 3
NCBI Official Symbol
SMPD3
NCBI Official Synonym Symbols
NSMASE2
UniProt Protein Name
Sphingomyelin phosphodiesterase 3
UniProt Synonym Protein Names
Neutral sphingomyelinase 2; nSMase-2; nSMase2; Neutral sphingomyelinase II
UniProt Gene Name
SMPD3
UniProt Synonym Gene Names
nSMase-2; nSMase2
NCBI Protein Information
sphingomyelin phosphodiesterase 3

UniProt Comments for N-SMase2

Catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these 2 cellular events independently. Also hydrolyzes sphingosylphosphocholine. Regulates the cell cycle by acting as a growth suppressor in confluent cells. Probably acts as a regulator of postnatal development and participates in bone and dentin mineralization.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-N-SMase2 antibody

 Reference Product  PubMed Publications
 SMPD1 antibody  >3 publications with N-SMase2 and SMPD1
 UGCG antibody  >1 publications with N-SMase2 and UGCG
 SMPD2 antibody  >1 publications with N-SMase2 and SMPD2

Pathways associated with anti-N-SMase2 antibody

 Products by Pathway  Pathway Diagram
 Ceramide Signaling Pathway antibodies  Ceramide Signaling Pathway Diagram
 Glycosphingolipid Metabolism Pathway antibodies  Glycosphingolipid Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Sphingolipid Metabolism Pathway antibodies  Sphingolipid Metabolism Pathway Diagram
 Sphingolipid Metabolism Pathway antibodies  Sphingolipid Metabolism Pathway Diagram
 Sphingolipid Metabolism Pathway antibodies  Sphingolipid Metabolism Pathway Diagram
 Sphingomyelin Metabolism/ceramide Salvage Pathway antibodies  Sphingomyelin Metabolism/ceramide Salvage Pathway Diagram

Diseases associated with anti-N-SMase2 antibody

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >14 publications with N-SMase2 and Necrosis
 Neoplasms Antibodies  >12 publications with N-SMase2 and Neoplasms
 Inflammation Antibodies  >8 publications with N-SMase2 and Inflammation
 Disease Models, Animal Antibodies  >6 publications with N-SMase2 and Disease Models, Animal
 Nervous System Diseases Antibodies  >6 publications with N-SMase2 and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >2 publications with N-SMase2 and Cardiovascular Diseases
 Neurodegenerative Diseases Antibodies  >2 publications with N-SMase2 and Neurodegenerative Diseases
 Carcinoma Antibodies  >2 publications with N-SMase2 and Carcinoma
 Fatty Liver Antibodies  >2 publications with N-SMase2 and Fatty Liver
 Learning Disorders Antibodies  >1 publications with N-SMase2 and Learning Disorders

Organs/Tissues associated with anti-N-SMase2 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >11 publications with N-SMase2 and Brain
 Lung Antibodies  >7 publications with N-SMase2 and Lung
 Muscle Antibodies  >7 publications with N-SMase2 and Muscle
 Bone Antibodies  >6 publications with N-SMase2 and Bone
 Blood Antibodies  >4 publications with N-SMase2 and Blood
 Embryonic Tissue Antibodies  >3 publications with N-SMase2 and Embryonic Tissue
 Connective Tissue Antibodies  >3 publications with N-SMase2 and Connective Tissue
 Nerve Antibodies  >2 publications with N-SMase2 and Nerve
 Adipose Tissue Antibodies  >2 publications with N-SMase2 and Adipose Tissue
 Skin Antibodies  >1 publications with N-SMase2 and Skin