Anti-N-SMase2 Antibody
Cat# MBS8291535-0,1mL
Size : 0.1mL
Brand : MyBiosource
N-SMase2 Antibody – Rabbit Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8291535MBS8291535 is an antibody targeting N-SMase2. Reactive in Human, Mouse, Rat. Host: Rabbit. Rabbit polyclonal antibody to N-SMase2 More details
Product Overview
Online Datasheet in PDFProduct Name
N-SMase2, Polyclonal Antibody
Full Product Name
Anti-N-SMase2 Antibody
Product Gene Name
anti-N-SMase2 antibody
Product Synonym Gene Name
SMPD3
Product Synonym Names
Sphingomyelin phosphodiesterase 3; Neutral sphingomyelinase 2; nSMase-2; nSMase2; Neutral sphingomyelinase II
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
Purified by immunogen affinity chromatography
Specificity
Recognizes endogenous levels of N-SMase2 protein.
Preparation and Storage
Upon receipt aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
Applications Tested/Suitable for anti-N-SMase2 antibody
Western Blot (WB)
Application Notes for anti-N-SMase2 antibody
WB: 1/500 - 1/2000
Other Notes
Small volumes of anti-N-SMase2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for N-SMase2. It may not necessarily be applicable to this product.
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
sphingomyelin phosphodiesterase 3
NCBI Official Synonym Full Names
sphingomyelin phosphodiesterase 3
NCBI Official Symbol
SMPD3
NCBI Official Synonym Symbols
NSMASE2
UniProt Protein Name
Sphingomyelin phosphodiesterase 3
UniProt Synonym Protein Names
Neutral sphingomyelinase 2; nSMase-2; nSMase2; Neutral sphingomyelinase II
UniProt Gene Name
SMPD3
UniProt Synonym Gene Names
nSMase-2; nSMase2
NCBI Protein Information
sphingomyelin phosphodiesterase 3
UniProt Comments for N-SMase2
Catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these 2 cellular events independently. Also hydrolyzes sphingosylphosphocholine. Regulates the cell cycle by acting as a growth suppressor in confluent cells. Probably acts as a regulator of postnatal development and participates in bone and dentin mineralization.
Show more Research Articles on N-SMase2
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with anti-N-SMase2 antibody
| Reference Product | PubMed Publications |
|---|---|
| SMPD1 antibody | >3 publications with N-SMase2 and SMPD1 |
| UGCG antibody | >1 publications with N-SMase2 and UGCG |
| SMPD2 antibody | >1 publications with N-SMase2 and SMPD2 |
Pathways associated with anti-N-SMase2 antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Ceramide Signaling Pathway antibodies | Ceramide Signaling Pathway Diagram |
| Glycosphingolipid Metabolism Pathway antibodies | Glycosphingolipid Metabolism Pathway Diagram |
| Metabolism Pathway antibodies | Metabolism Pathway Diagram |
| Metabolism Of Lipids And Lipoproteins Pathway antibodies | Metabolism Of Lipids And Lipoproteins Pathway Diagram |
| Sphingolipid Metabolism Pathway antibodies | Sphingolipid Metabolism Pathway Diagram |
| Sphingolipid Metabolism Pathway antibodies | Sphingolipid Metabolism Pathway Diagram |
| Sphingolipid Metabolism Pathway antibodies | Sphingolipid Metabolism Pathway Diagram |
| Sphingomyelin Metabolism/ceramide Salvage Pathway antibodies | Sphingomyelin Metabolism/ceramide Salvage Pathway Diagram |
Diseases associated with anti-N-SMase2 antibody
| Disease Name | Pubmed Publications |
|---|---|
| Necrosis Antibodies | >14 publications with N-SMase2 and Necrosis |
| Neoplasms Antibodies | >12 publications with N-SMase2 and Neoplasms |
| Inflammation Antibodies | >8 publications with N-SMase2 and Inflammation |
| Disease Models, Animal Antibodies | >6 publications with N-SMase2 and Disease Models, Animal |
| Nervous System Diseases Antibodies | >6 publications with N-SMase2 and Nervous System Diseases |
| Cardiovascular Diseases Antibodies | >2 publications with N-SMase2 and Cardiovascular Diseases |
| Neurodegenerative Diseases Antibodies | >2 publications with N-SMase2 and Neurodegenerative Diseases |
| Carcinoma Antibodies | >2 publications with N-SMase2 and Carcinoma |
| Fatty Liver Antibodies | >2 publications with N-SMase2 and Fatty Liver |
| Learning Disorders Antibodies | >1 publications with N-SMase2 and Learning Disorders |
Organs/Tissues associated with anti-N-SMase2 antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Brain Antibodies | >11 publications with N-SMase2 and Brain |
| Lung Antibodies | >7 publications with N-SMase2 and Lung |
| Muscle Antibodies | >7 publications with N-SMase2 and Muscle |
| Bone Antibodies | >6 publications with N-SMase2 and Bone |
| Blood Antibodies | >4 publications with N-SMase2 and Blood |
| Embryonic Tissue Antibodies | >3 publications with N-SMase2 and Embryonic Tissue |
| Connective Tissue Antibodies | >3 publications with N-SMase2 and Connective Tissue |
| Nerve Antibodies | >2 publications with N-SMase2 and Nerve |
| Adipose Tissue Antibodies | >2 publications with N-SMase2 and Adipose Tissue |
| Skin Antibodies | >1 publications with N-SMase2 and Skin |


