Tamanho : 1kit
| Product Data | |
| Format | 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control |
|---|---|
| Vector | RFP-BSD |
| Target Symbol | SNF5 |
| Locus ID | 6598 |
| Components | KN217885G1, SNF5 gRNA vector 1 in pCas-Guide CRISPR vector KN217885G2, SNF5 gRNA vector 2 in pCas-Guide CRISPR vector KN217885RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette. GE100003, scramble sequence in pCas-Guide vector |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
| Reference Data | |
| RefSeq | NM_001007468, NM_001317946, NM_003073, NM_001362877 |
| UniProt ID | Q12824 |
| Synonyms | BAF47; CSS3; hSNFS; INI1; MRD15; PPP1R144; RDT; RTPS1; Sfh1p; SNF5; SNF5L1; Snr1; SWNTS1 |
| Summary | The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Alternatively spliced transcript variants have been found for this gene. provided by RefSeq, Dec 2015 |
| Shipping | Ambient |
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| SDS |
| SKU | Description | Size | ||
|---|---|---|---|---|
| GA104512 | SMARCB1 CRISPRa kit - CRISPR gene activation of human SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 | 1 kit | | |
| KN217885 | SMARCB1 - human gene knockout kit via CRISPR, HDR mediated | 1 kit | | |
| KN217885BN | SMARCB1 - human gene knockout kit via CRISPR, HDR mediated | 1 kit | | |
| KN217885LP | SMARCB1 - human gene knockout kit via CRISPR, HDR mediated | 1 kit | | |
| KN417885 | SMARCB1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |