SNF5 (SMARCB1) Human Gene Knockout Kit (CRISPR)

Cat# KN217885RB

Size : 1kit


SNF5 (SMARCB1) Human Gene Knockout Kit (CRISPR)

Be the first to review this product
SKU
KN217885RB
SMARCB1 - human gene knockout kit via CRISPR, HDR mediated
 
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol SNF5
Locus ID 6598
Components

KN217885G1, SNF5 gRNA vector 1 in pCas-Guide CRISPR vector

KN217885G2, SNF5 gRNA vector 2 in pCas-Guide CRISPR vector

KN217885RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001007468, NM_001317946, NM_003073, NM_001362877
UniProt ID Q12824
Synonyms BAF47; CSS3; hSNFS; INI1; MRD15; PPP1R144; RDT; RTPS1; Sfh1p; SNF5; SNF5L1; Snr1; SWNTS1
Summary The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Alternatively spliced transcript variants have been found for this gene. provided by RefSeq, Dec 2015
Shipping Ambient
SKU Description Size
GA104512 SMARCB1 CRISPRa kit - CRISPR gene activation of human SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 1 kit
KN217885 SMARCB1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
KN217885BN SMARCB1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
KN217885LP SMARCB1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
KN417885 SMARCB1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.