Anti-Centrin-2 Antibody
Cat# MBS8245362-0,1mL
Size : 0.1mL
Brand : MyBiosource
Western blot analysis of Centrin-2 expression in HT29 (A), MCF7 (B), mouse spleen (C) whole cell lysates.
Immunofluorescent analysis of Centrin-2 staining in MCF7 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.
Centrin-2 (CETN2) Antibody – Rabbit Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8245362MBS8245362 is an antibody targeting CETN2. Also known as Anti-Centrin-2 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit. Rabbit polyclonal antibody to Centrin-2 More details
Product Overview
Online Datasheet in PDFProduct Name
Centrin-2 (CETN2), Polyclonal Antibody
Full Product Name
Anti-Centrin-2 Antibody
Product Gene Name
anti-CETN2 antibody
Product Synonym Names
CALT; CEN2; Centrin-2; Caltractin isoform 1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of Centrin-2 protein.
Preparation and Storage
Upon delivery aliquot and store at -20°C. Avoid freeze/thaw cycles.
Applications Tested/Suitable for anti-CETN2 antibody
Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
Application Notes for anti-CETN2 antibody
WB: 1/500 - 1/2000; IF/ICC: 1/50 - 1/200
Immunofluorescence (IF) of anti-CETN2 antibody
Immunofluorescent analysis of Centrin-2 staining in MCF7 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.
Other Notes
Small volumes of anti-CETN2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for CETN2. It may not necessarily be applicable to this product.
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
centrin-2
NCBI Official Synonym Full Names
centrin 2
NCBI Official Symbol
CETN2
NCBI Official Synonym Symbols
CALT; CEN2
UniProt Protein Name
Centrin-2
UniProt Synonym Protein Names
Caltractin isoform 1
Protein Family
Centrin
UniProt Gene Name
CETN2
UniProt Synonym Gene Names
CALT; CEN2
UniProt Entry Name
CETN2_HUMAN
NCBI Protein Information
centrin-2
NCBI Summary for CETN2
Caltractin belongs to a family of calcium-binding proteins and is a structural component of the centrosome. The high level of conservation from algae to humans and its association with the centrosome suggested that caltractin plays a fundamental role in the structure and function of the microtubule-organizing center, possibly required for the proper duplication and segregation of the centrosome. [provided by RefSeq, Jul 2008]
Show more UniProt Comments for CETN2
CETN2: a calcium-binding proteins and is a structural component of the centrosome. Contains 4 EF-hand calcium-binding domains. Highly conserved from algae to humans. Its association with the centrosome suggests that it plays a fundamental role in the structure and function of the microtubule-organizing center, possibly required for the proper duplication and segregation of the centrosome.
Protein type: Calcium-binding; Cell cycle regulation; DNA repair, damage
Chromosomal Location of Human Ortholog: Xq28
Cellular Component: centriole; centrosome; cytosol; intracellular; nucleoplasm; photoreceptor connecting cilium
Molecular Function: calcium ion binding; G-protein beta/gamma-subunit binding; heterotrimeric G-protein binding; microtubule binding; protein binding
Biological Process: cell division; centriole replication; G2/M transition of mitotic cell cycle; mitosis; nucleotide-excision repair; nucleotide-excision repair, DNA damage recognition; nucleotide-excision repair, DNA duplex unwinding; nucleotide-excision repair, preincision complex assembly; protein sumoylation; regulation of cytokinesis; spermatogenesis
Show more Protein type: Calcium-binding; Cell cycle regulation; DNA repair, damage
Chromosomal Location of Human Ortholog: Xq28
Cellular Component: centriole; centrosome; cytosol; intracellular; nucleoplasm; photoreceptor connecting cilium
Molecular Function: calcium ion binding; G-protein beta/gamma-subunit binding; heterotrimeric G-protein binding; microtubule binding; protein binding
Biological Process: cell division; centriole replication; G2/M transition of mitotic cell cycle; mitosis; nucleotide-excision repair; nucleotide-excision repair, DNA damage recognition; nucleotide-excision repair, DNA duplex unwinding; nucleotide-excision repair, preincision complex assembly; protein sumoylation; regulation of cytokinesis; spermatogenesis
Research Articles on CETN2
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with anti-CETN2 antibody
| Reference Product | PubMed Publications |
|---|---|
| XPC antibody | >24 publications with CETN2 and XPC |
| RAD23B antibody | >6 publications with CETN2 and RAD23B |
| POLE antibody | >3 publications with CETN2 and POLE |
| SFI1 antibody | >3 publications with CETN2 and SFI1 |
| XRCC6 antibody | >1 publications with CETN2 and XRCC6 |
| PRKDC antibody | >1 publications with CETN2 and PRKDC |
Pathways associated with anti-CETN2 antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| AURKA Activation By TPX2 Pathway antibodies | AURKA Activation By TPX2 Pathway Diagram |
| Anchoring Of The Basal Body To The Plasma Membrane Pathway antibodies | Anchoring Of The Basal Body To The Plasma Membrane Pathway Diagram |
| Assembly Of The Primary Cilium Pathway antibodies | Assembly Of The Primary Cilium Pathway Diagram |
| Cell Cycle Pathway antibodies | Cell Cycle Pathway Diagram |
| Cell Cycle, Mitotic Pathway antibodies | Cell Cycle, Mitotic Pathway Diagram |
| Centrosome Maturation Pathway antibodies | Centrosome Maturation Pathway Diagram |
| DNA Damage Recognition In GG-NER Pathway antibodies | DNA Damage Recognition In GG-NER Pathway Diagram |
| DNA Repair Pathway antibodies | DNA Repair Pathway Diagram |
| Formation Of Incision Complex In GG-NER Pathway antibodies | Formation Of Incision Complex In GG-NER Pathway Diagram |
| G2/M Transition Pathway antibodies | G2/M Transition Pathway Diagram |
Diseases associated with anti-CETN2 antibody
| Disease Name | Pubmed Publications |
|---|---|
| Precancerous Conditions Antibodies | >5 publications with CETN2 and Precancerous Conditions |
| Chromosome Aberrations Antibodies | >4 publications with CETN2 and Chromosome Aberrations |
| Adenocarcinoma Antibodies | >2 publications with CETN2 and Adenocarcinoma |
| Breast Neoplasms Antibodies | >2 publications with CETN2 and Breast Neoplasms |
| Lung Neoplasms Antibodies | >1 publications with CETN2 and Lung Neoplasms |
| Kidney Diseases Antibodies | >1 publications with CETN2 and Kidney Diseases |
| Cell Transformation, Neoplastic Antibodies | >1 publications with CETN2 and Cell Transformation, Neoplastic |
| Immune System Diseases Antibodies | >1 publications with CETN2 and Immune System Diseases |
| Nervous System Diseases Antibodies | >1 publications with CETN2 and Nervous System Diseases |
| Lung Diseases Antibodies | >1 publications with CETN2 and Lung Diseases |
Organs/Tissues associated with anti-CETN2 antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Eye Antibodies | >4 publications with CETN2 and Eye |
| Brain Antibodies | >3 publications with CETN2 and Brain |
| Testis Antibodies | >2 publications with CETN2 and Testis |
| Blood Antibodies | >1 publications with CETN2 and Blood |
| Ovary Antibodies | >1 publications with CETN2 and Ovary |
| Prostate Antibodies | >1 publications with CETN2 and Prostate |
| Pancreas Antibodies | >1 publications with CETN2 and Pancreas |
| Kidney Antibodies | >1 publications with CETN2 and Kidney |
| Lung Antibodies | >1 publications with CETN2 and Lung |