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> Anti-Notch1 Antibody (8D225)

Anti-Notch1 Antibody (8D225)

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Cat# NB-64-159506-50uL

Size : 50uL

Brand : Neo Biotech


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Anti-Notch1 Monoclonal Antibody (8D225)

(Synonyms: Translocation-associated notch protein TAN-1, TAN1, NOTCH1, Notch 1, Neurogenic locus notch homolog protein 1, hN1) Copy Product Info

Synonyms: Translocation-associated notch protein TAN-1, TAN1, NOTCH1, Notch 1, Neurogenic locus notch homolog protein 1, hN1

Catalog No. TMAB-09570 Copy Product Info
Anti-Notch1 Monoclonal Antibody (8D225) is a Rabbit antibody targeting Notch1. Anti-Notch1 Monoclonal Antibody (8D225) can be used in WB,IHC-P,ICC/IF,FCM.
For research use only—not for human use. No sales to individuals. Use as intended only.

Product Information

Bioactivity
Description
Anti-Notch1 Monoclonal Antibody (8D225) is a Rabbit antibody targeting Notch1. Anti-Notch1 Monoclonal Antibody (8D225) can be used in WB,IHC-P,ICC/IF,FCM.
SynonymsTranslocation-associated notch protein TAN-1, TAN1, NOTCH1, Notch 1, Neurogenic locus notch homolog protein 1, hN1
Ig Type
IgG
Clone
8D225
Reactivity
Human,Mouse,Rat
Application
WB
IHC-P
ICC/IF
FCM
Recommended Dose
WB: 1:1000-1:10000; IHC: 1:50-1:200; IF: 1:50-1:200; FCM: 1:50-1:100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Monoclonal Antibody
PurificationAffinity Chromatography
AppearanceLiquid
Formulation10 mM PBS, pH 7.4, 150 mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol
Research BackgroundFunctions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthesized peptide derived from human Notch1
Antigen Species
Human
Gene Name
NOTCH1
Gene ID
4851
Protein Name
Neurogenic locus notch homolog protein 1
Uniprot ID
P46531
Biology Area
Neuroscience
Chemical Properties
Molecular WeightCalculated MW: 273 kDa; Observed MW: 125 kDa
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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