CD45RO antibody [UCHL1] (APC)
Cat. No. GTX79857
Cat. No. GTX79857
![Anti-CD45RO antibody [UCHL1] (APC) used in Flow cytometry (FCM). GTX79857](/proxy_img/aHR0cDovL3d3dy5nZW5ldGV4LmNvbS91cGxvYWQvd2Vic2l0ZS9wcm91Y3RfaW1nL21pZGRsZS9HVFg3OTg1Ny9HVFg3OTg1N18yMDIwMTAyMF9GQUNTXzEwX3dfMjMwNjEzMjJfNjcwLndlYnA=.webp)
GTX79857 FCM Image
FACS analysis of human peripheral blood lymphocytes using GTX79857 CD45RO antibody [UCHL1] (APC).
Solid line : Primary antibody
Dashed line : APC mouse IgG2a isotype control
Antibody amount : 0.25 μg
Summary
The UCHL1 antibody reacts with the human CD45 isoform known as CD45RO, a protein tyrosine phosphatase of ≥ 220 kDa. CD45 is one of the most abundant hematopoietic markers, and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). Various isoforms are generated and expressed in cell-specific patterns. With their broad cell distribution, CD45 isoforms are critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA and CD45RB.