Cedazuridine [1141397-80-9]
Cat# T26972-10mg
Size : 10mg
Brand : TargetMol
Cedazuridine
(Synonyms: (4R)-2'-Deoxy-2',2'-difluoro-3,4,5,6-tetrahydrouridine) Copy Product Info
Cedazuridine ((4R)-2'-Deoxy-2',2'-difluoro-3,4,5,6-tetrahydrouridine) is an oral inhibitor of cytidine deaminase with antineoplastic properties.
Cas No. 1141397-80-9
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Purity:99.66%
Appearance:Solid
Color:White
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Chemical Properties
Storage & Solubility Information
| Description | Cedazuridine ((4R)-2'-Deoxy-2',2'-difluoro-3,4,5,6-tetrahydrouridine) is an oral inhibitor of cytidine deaminase with antineoplastic properties. |
| In vivo | Oral Cedazuridine when combined with Azacitidine achieves successful tumor regression in both human cell line-derived xenograft transplantation experiment and patient-derived xenograft models[2]. |
| Synonyms | (4R)-2'-Deoxy-2',2'-difluoro-3,4,5,6-tetrahydrouridine |
| Molecular Weight | 268.21 |
| Formula | C9H14F2N2O5 |
| Cas No. | 1141397-80-9 |
| Smiles | OC[C@H]1O[C@@H](N2CC[C@@H](O)NC2=O)C(F)(F)[C@@H]1O |
| Relative Density. | no data available |
| Storage | Keep away from direct sunlight,Store at low temperature, Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 17.6 mg/mL (65.62 mM), Sonication is recommended.  | ||||||||||||||||||||||||||||||
| In Vivo Formulation | 10% DMSO+90% Saline: 1.76 mg/mL (6.56 mM), Solution. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density. | |||||||||||||||||||||||||||||||