Reagents and instruments for immunology, cell biology and molecular biology.

Cholic acid-Biotin

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Cat# NB-64-109759-5mg

Size : 5mg

Brand : Neo Biotech

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Cholic acid-Biotin

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Synonyms:

Catalog No. T210309 Copy Product Info

Purity: 99.87%

Cholic acid-Biotin is a biotinylated derivative of cholic acid, a primary bile acid synthesized in the liver and typically conjugated with glycine or taurine to facilitate fat absorption and cholesterol excretion. The incorporation of a biotin moiety enables affinity-based purification and detection strategies, making this conjugate useful in studies of bile acid transport, receptor interactions, and biomolecule tagging in biochemical assays.

For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.87%

ee:100%

Appearance:Solid

Color:White

Product Introduction

Bioactivity

Description	Cholic acid-Biotin is a biotinylated derivative of cholic acid, a primary bile acid synthesized in the liver and typically conjugated with glycine or taurine to facilitate fat absorption and cholesterol excretion. The incorporation of a biotin moiety enables affinity-based purification and detection strategies, making this conjugate useful in studies of bile acid transport, receptor interactions, and biomolecule tagging in biochemical assays.

Chemical Properties

Molecular Weight	809.12
Formula	C₄₂H₇₂N₄O₉S
Smiles	O[C@@H]1CC[C@@]2(C)[C@@](C[C@@H](O)[C@]3(23)[C@]2(23)C[C@H](O)[C@@]4(C)[C@@]3(23)CC[C@@]4([C@H](C)CCC(NCCOCCOCCOCCNC(CCCC[C@H]5[C@@H](NC6=O)[C@@H](N6)CS5)=O)=O)23)(23)C1

Storage & Solubility Information

Storage

Keep away from direct sunlight Store at -20°C Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (98.87 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.2359 mL	6.1796 mL	12.3591 mL	61.7955 mL
5 mM	0.2472 mL	1.2359 mL	2.4718 mL	12.3591 mL
10 mM	0.1236 mL	0.6180 mL	1.2359 mL	6.1796 mL
20 mM	0.0618 mL	0.3090 mL	0.6180 mL	3.0898 mL
50 mM	0.0247 mL	0.1236 mL	0.2472 mL	1.2359 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

Related Tags: Cholic acid-Biotin chemical structure | Cholic acid-Biotin formula | Cholic acid-Biotin molecular weight