Duvelisib hydrate
Cat# orb1738678-5mg
Size : 5mg
Brand : Biorbyt
Contact local distributor :
Phone : +1 850 650 7790
Duvelisib hydrate
Catalog Number: orb1738678
| Catalog Number | orb1738678 |
|---|---|
| Category | Small Molecules |
| Description | Duvelisib hydrate |
| CAS Number | 1386861-49-9 |
| Purity | 0.98 |
| MW | 434.884 |
| SMILES | O.C[C@H](Nc1ncnc2nc[nH]c12)c1cc2cccc(Cl)c2c(=O)n1-c1ccccc1 |
| Formula | C22H19ClN6O2 |
| Biological Activity | Duvelisib, also known as IPI-145 and INK-1197, is an orally bioavailable, highly selective and potent small molecule inhibitor of the delta and gamma isoforms of phosphoinositide-3 kinase (PI3K) with potential immunomodulating and antineoplastic activities. Upon administration, PI3K delta/gamma inhibitor IPI 145 prevents the activation of the PI3K delta/gamma-mediated signaling pathways which may lead to a reduction in cellular proliferation in PI3K delta/gamma-expressing tumor cells. Unlike other isoforms of PI3K, the delta and gamma isoforms are overexpressed primarily in hematologic malignancies and inflammatory and autoimmune diseases. |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |