Epratuzumab [205923-57-5]
Cat# T76805-1mg
Size : 1mg
Brand : TargetMol
Epratuzumab
(Synonyms: Anti-Human CD22 Recombinant Antibody, Antibody hLL 2, AMG41, AMG 41) Copy Product InfoEpratuzumab (AMG 41) is a humanized monoclonal antibody targeting CD22, also a tumor imaging agent that induces CD22 phosphorylation. It is used in autoimmune disease research.
Cas No. 205923-57-5
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:>95.0% (SDS-PAGE); 99.37% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
COA SDS-PAGE HPLC Instruction Manual of Inhibitory Antibody
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Antibody Information
Storage & Solubility Information
| Description | Epratuzumab (AMG 41) is a humanized monoclonal antibody targeting CD22, also a tumor imaging agent that induces CD22 phosphorylation. It is used in autoimmune disease research. |
| In vitro | Epratuzumab binds to the CD22 extracellular domain with an affinity of K (D) = 0.7 nM. Epratuzumab binds to B cell lines or primary B cells from patients with NHL, resulting in rapid internalization of the CD22/ antibody complex. [1] |
| Synonyms | Anti-Human CD22 Recombinant Antibody, Antibody hLL 2, AMG41, AMG 41 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | 933 |
| Uniprot ID | P20273 |
| Target | Siglec-2/CD22 |
| Molecular Weight | 146.58 kDa |
| Cas No. | 205923-57-5 |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control | Human IgG1 kappa, Isotype Control |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |