• Specifications

    Product Description

    Histone Demethylase (H3-K4 Specific) Activity/Inhibition Assay Kit is use for measuring activity/inhibition of H3-K4 specific histone demethylases using cell/ tissue extracts.

    Regulation Status

    For research use only (RUO)

    Storage Instruction

    Store HD3, HD4, HD6 and HD7 at -20°C away from light. Store all other components at 4°C away from light.

  • Applications

    Functional Study

  • Gene Info — AOF2

    Entrez GeneID

    23028

    Gene Name

    AOF2

    Gene Alias

    BHC110, KDM1, KIAA0601, LSD1

    Gene Description

    amine oxidase (flavin containing) domain 2

    Omim ID

    609132

    Gene Ontology

    Hyperlink

    Gene Summary

    This gene encodes a nuclear protein containing a SWIRM domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. Alternative splicing results in multiple transcript variants. [provided by RefSeq

    Other Designations

    BRAF35-HDAC complex protein BHC110|FAD-binding protein BRAF35-HDAC complex, 110 kDa subunit|lysine (K)-specific demethylase 1|lysine-specific histone demethylase 1

  • Interactomes