HRP-Linked Polyclonal Antibody to Prostaglandin Endoperoxide Synthase 2 (PTGS2)
Cat# MBS2046279-0,5mL
Size : 0.5mL
Brand : MyBiosource
Knockout Validation: Lane 1: Wild-type RAW264.7 cell lysate; Lane 2: PTGS2 knockout RAW264.7 cell lysate; Predicted MW: 69kd Observed MW: 69kd Primary Ab: 5ug/ml Rabbit Anti-Human PTGS2 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (#MBS2086047)
Prostaglandin Endoperoxide Synthase 2 (PTGS2) Antibody – Rabbit Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2046279SPECIAL PROMOTION: Get FREE Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment
MBS2046279 is an antibody targeting PTGS2. Also known as HRP-Linked Polyclonal Antibody to Prostaglandin Endoperoxide Synthase 2 (PTGS2). Reactive in Human, Mouse. Host: Rabbit. More details
Product Overview
Online Datasheet in PDFProduct Name
Prostaglandin Endoperoxide Synthase 2 (PTGS2), Polyclonal Antibody
Full Product Name
HRP-Linked Polyclonal Antibody to Prostaglandin Endoperoxide Synthase 2 (PTGS2)
Product Gene Name
anti-PTGS2 antibody
Product Synonym Names
PGG/HS; PGHS2; PHS2; HCox2; COX2; Cyclooxygenase 2; Prostaglandin G/H Synthase And Cyclooxygenase; Prostaglandin H2 synthase 2
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse
Concentration
500ug/ml (lot specific)
Matching Pairs
Unconjugated Antibody: PTGS2 (MBS2026131)
HRP Conjugated Antibody: PTGS2 (MBS2046279)
HRP Conjugated Antibody: PTGS2 (MBS2046279)
Matching Pairs
HRP Conjugated Antibody: PTGS2 (MBS2046279)
Immunogen: PTGS2 (MBS2031686)
Immunogen: PTGS2 (MBS2031686)
Molecular Weight
68,996 Da
OMIM
L15326 mRNA
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Immunogen
PTGS2 (Phe187~Asn425)
Conjugation
HRP
Cross Reactivity
Human, Mouse
Unconjugated Antibody
The unconjugated antibody version of this item is also available as catalog #MBS2026131
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-PTGS2 antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA)
Knockout Validation of anti-PTGS2 antibody
Knockout Validation: Lane 1: Wild-type RAW264.7 cell lysate; Lane 2: PTGS2 knockout RAW264.7 cell lysate; Predicted MW: 69kd Observed MW: 69kd Primary Ab: 5ug/ml Rabbit Anti-Human PTGS2 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (#MBS2086047)
Other Notes
Small volumes of anti-PTGS2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for PTGS2. It may not necessarily be applicable to this product.
NCBI Official Full Name
prostaglandin endoperoxide synthase-2
NCBI Official Synonym Full Names
prostaglandin-endoperoxide synthase 2
NCBI Official Symbol
PTGS2
NCBI Official Synonym Symbols
COX2; COX-2; PHS-2; PGG/HS; PGHS-2; hCox-2; GRIPGHS
UniProt Protein Name
Prostaglandin G/H synthase 2
UniProt Synonym Protein Names
Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2
Protein Family
Prostaglandin G/H synthase
UniProt Gene Name
PTGS2
UniProt Synonym Gene Names
COX2; COX-2; PGH synthase 2; PGHS-2
NCBI Protein Information
prostaglandin G/H synthase 2
NCBI Summary for PTGS2
Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009]
Show more UniProt Comments for PTGS2
COX-2: Mediates the formation of prostaglandins from arachidonate. May have a role as a major mediator of inflammation and/or a role for prostanoid signaling in activity-dependent plasticity. Homodimer. Belongs to the prostaglandin G/H synthase family.
Protein type: EC 1.14.99.1; Lipid Metabolism - arachidonic acid; Oxidoreductase
Chromosomal Location of Human Ortholog: 1q31.1
Cellular Component: cytoplasm; endoplasmic reticulum; endoplasmic reticulum lumen; endoplasmic reticulum membrane; neuron projection; nucleus
Molecular Function: arachidonate 15-lipoxygenase activity; enzyme binding; heme binding; peroxidase activity; prostaglandin-endoperoxide synthase activity; protein binding
Biological Process: cell motility; cyclooxygenase pathway; lipoxygenase pathway; nicotinamide metabolic process; positive regulation of fever; positive regulation of nitric oxide biosynthetic process; prostaglandin biosynthetic process; prostaglandin metabolic process; regulation of blood pressure
Show more Protein type: EC 1.14.99.1; Lipid Metabolism - arachidonic acid; Oxidoreductase
Chromosomal Location of Human Ortholog: 1q31.1
Cellular Component: cytoplasm; endoplasmic reticulum; endoplasmic reticulum lumen; endoplasmic reticulum membrane; neuron projection; nucleus
Molecular Function: arachidonate 15-lipoxygenase activity; enzyme binding; heme binding; peroxidase activity; prostaglandin-endoperoxide synthase activity; protein binding
Biological Process: cell motility; cyclooxygenase pathway; lipoxygenase pathway; nicotinamide metabolic process; positive regulation of fever; positive regulation of nitric oxide biosynthetic process; prostaglandin biosynthetic process; prostaglandin metabolic process; regulation of blood pressure
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with anti-PTGS2 antibody
| Reference Product | PubMed Publications |
|---|---|
| JUN antibody | >2734 publications with PTGS2 and JUN |
| PLA2G4A antibody | >298 publications with PTGS2 and PLA2G4A |
| ALOX5 antibody | >273 publications with PTGS2 and ALOX5 |
| MAPK1 antibody | >254 publications with PTGS2 and MAPK1 |
| FOS antibody | >231 publications with PTGS2 and FOS |
| PTGES antibody | >46 publications with PTGS2 and PTGES |
| CYP2E1 antibody | >34 publications with PTGS2 and CYP2E1 |
| MAPK14 antibody | >8 publications with PTGS2 and MAPK14 |
| PTGDS antibody | >6 publications with PTGS2 and PTGDS |
| PLA2G1B antibody | >3 publications with PTGS2 and PLA2G1B |
Pathways associated with anti-PTGS2 antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Arachidonic Acid Metabolism Pathway antibodies | Arachidonic Acid Metabolism Pathway Diagram |
| Arachidonic Acid Metabolism Pathway antibodies | Arachidonic Acid Metabolism Pathway Diagram |
| Arachidonic Acid Metabolism Pathway antibodies | Arachidonic Acid Metabolism Pathway Diagram |
| C-MYB Transcription Factor Network Pathway antibodies | C-MYB Transcription Factor Network Pathway Diagram |
| C20 Prostanoid Biosynthesis Pathway antibodies | C20 Prostanoid Biosynthesis Pathway Diagram |
| Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway antibodies | Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway Diagram |
| Calcium Signaling In The CD4+ TCR Pathway antibodies | Calcium Signaling In The CD4+ TCR Pathway Diagram |
| Chemical Carcinogenesis Pathway antibodies | Chemical Carcinogenesis Pathway Diagram |
| Chemical Carcinogenesis Pathway antibodies | Chemical Carcinogenesis Pathway Diagram |
| Defective AMN Causes Hereditary Megaloblastic Anemia 1 Pathway antibodies | Defective AMN Causes Hereditary Megaloblastic Anemia 1 Pathway Diagram |
Diseases associated with anti-PTGS2 antibody
| Disease Name | Pubmed Publications |
|---|---|
| Inflammation Antibodies | >6224 publications with PTGS2 and Inflammation |
| Carcinoma Antibodies | >3031 publications with PTGS2 and Carcinoma |
| Nervous System Diseases Antibodies | >2206 publications with PTGS2 and Nervous System Diseases |
| Colorectal Neoplasms Antibodies | >1685 publications with PTGS2 and Colorectal Neoplasms |
| Adenocarcinoma Antibodies | >1437 publications with PTGS2 and Adenocarcinoma |
| Skin Diseases Antibodies | >1149 publications with PTGS2 and Skin Diseases |
| Lung Diseases Antibodies | >1011 publications with PTGS2 and Lung Diseases |
| Colonic Neoplasms Antibodies | >952 publications with PTGS2 and Colonic Neoplasms |
| Edema Antibodies | >897 publications with PTGS2 and Edema |
| Breast Neoplasms Antibodies | >732 publications with PTGS2 and Breast Neoplasms |
Organs/Tissues associated with anti-PTGS2 antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Blood Antibodies | >4660 publications with PTGS2 and Blood |
| Vascular Antibodies | >3122 publications with PTGS2 and Vascular |
| Brain Antibodies | >1991 publications with PTGS2 and Brain |
| Liver Antibodies | >1375 publications with PTGS2 and Liver |
| Muscle Antibodies | >1367 publications with PTGS2 and Muscle |
| Kidney Antibodies | >1231 publications with PTGS2 and Kidney |
| Stomach Antibodies | >1207 publications with PTGS2 and Stomach |
| Bone Antibodies | >1152 publications with PTGS2 and Bone |
| Intestine Antibodies | >1019 publications with PTGS2 and Intestine |
| Skin Antibodies | >945 publications with PTGS2 and Skin |